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Advances in the de novo design of coiled-coil proteins made by two different research groups proceeding by two different routes demonstrate that the range of protein nanostructures potentially available for various molecular machine systems is significantly larger than the range of such structures already exploited by natural selection.
A demonstration that most fundamental biological processes can be implemented in a test tube as efficiently as in live bacteria provides synthetic biology the tools to create a ‘new industrial revolution’, which may or may not lead to more general molecular manufacturing.
One possible pathway from current technology to advanced nanotechnology that will comprise atomically precise manufacturing implemented by atomically precise machinery is through adaptation and extension of the complex molecular machine systems evolved by biology. Synthetic biology, which engineers new biological systems and function not evolved in nature, is an intermediate stage along this path. An… Continue reading More complex circuits for synthetic biology lead toward engineered cells
Darpa has launched a “Living Foundries” program to bring an engineering perspective to synthetic biology to greatly accelerate progress through standardization and modularization.
RNA CAD tools developed for RNA-regulated control of gene expression in synthetic biology successfully engineered metabolic pathways in bacteria. Will engineering RNA-based genetic control systems lead to design tools for other RNA-based molecular machine systems?
Yesterday at the IFTF meeting (pdf) “Beyond the Horizon: Science and Technology in Ten, Twenty and Fifty Years” we heard from a leading synthetic biologist. In addition to describing this fascinating and potentially powerful new technology, he made a plea that it not be “re-militarized” (as biology was formerly, he said) and that we needed… Continue reading Synthetic biology and nanotech
Don’t miss out on Early Bird Tickets for Vision Weekend, at Bückeburg Palace, Germany, July 12-14th and in San Francisco, USA, December 6-8. This year’s theme is “Paths to Progress”, and we can’t wait to share the speakers we have already gathered in the coming days. Our aim is to bring our community… Continue reading Foresight Institute March Newsletter
Presenter William Shih, Harvard University William is overseeing an effort to apply Synthetic Biology approaches to the development of self-assembling DNA nanostructures and devices for use in biomedical applications. In addition to carrying genetic information, DNA is increasingly being explored for its use as a building material. This new process is called DNA origami because… Continue reading William Shih | Self Assembling DNA Nanostructures @ Molecular Systems Design Workshop 2023
Presenter Dr Brett J. Kagan, Chief Scientific Officer at Cortical Labs Dr Brett J. Kagan is the Chief Scientific Officer at Cortical Labs. Cortical Labs is a multidisciplinary deep-tech startup looking at integrating hardware, software, and synthetic biology approaches to explore how to harness intelligence from neurons on a chip. Dr Kagan has a PhD… Continue reading Brett Kagan | Brain Cells in a Dish as an Information Processing Device
Presenter Logan Collins, Washington University My name is Logan Thrasher Collins and I make science fiction into reality. I am a futurist, synthetic biologist, author, and innovator. I am also a 2023 Foresight Fellow. When I was 16, I invented a new antimicrobial protein, OpaL (Overexpressed protein aggregator Lipophilic). I next developed a bacterial conjugation… Continue reading Logan Collins | Mapping the Human Brain with Expansion X-ray Microscopy @ WBE Workshop 2023
