Nanobiotechnology

Engineered protein assembles molecules into atomically precise lattice

By | 2017-06-01T14:01:36-07:00 July 30th, 2016|Atomically Precise Manufacturing (APM), Bionanotechnology, Computational nanotechnology, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Research|

An engineered protein controls the assembly of C60 fullerene molecules into an atomically precise lattice that conducts electricity while neither component alone would.

Protein design provides a novel metabolic path for carbon fixation

By | 2017-06-01T14:01:36-07:00 June 8th, 2016|Atomically Precise Manufacturing (APM), Bionanotechnology, Computational nanotechnology, Energy, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Productive Nanosystems, Research|

Computational design of an enzyme that carboligates three one-carbon molecules to form one three-carbon molecule, an activity that does not exist in nature, provides proof-of-principle for a novel metabolic pathway for carbon fixation.

Triple helices stabilize macroscopic crystals for DNA nanotechnology

By | 2017-06-01T14:01:37-07:00 May 5th, 2016|Atomically Precise Manufacturing (APM), Bionanotechnology, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Productive Nanosystems, Research|

A DNA strand capable of forming a triple helix with a portion of the DNA double helices in a macroscopic DNA crystal enhances the weak interactions holding the crystal together so that the crystal remains stable in the absence of a high ionic strength environment.

DNA triplex formation decorates DNA crystals with sub-nanometer precision

By | 2017-06-01T14:01:37-07:00 May 3rd, 2016|Bionanotechnology, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Research|

A specially designed triplex forming oligonucleotide bearing a cargo molecule binds to a specific sequence in the major groove of a DNA double helix to form a modified DNA tile that self assembles into a macroscopic crystal in which each helix carries a cargo molecule positioned to sub-nanometer precision.

Macroscopic DNA crystals from molecular tensegrity triangles

By | 2017-06-01T14:16:59-07:00 May 2nd, 2016|Atomically Precise Manufacturing (APM), Bionanotechnology, Found On Web, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Research|

Structural DNA nanotechnology: progress toward a precise self-assembling three dimensional scaffold by building macroscopic crystals from nanoscale structures.

DNA nanotechnology defeats drug resistance in cancer cells

By | 2017-06-01T14:01:38-07:00 April 2nd, 2016|Bionanotechnology, Future Medicine, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Research|

Small, stiff, rectangular rods made using scaffolded DNA origami bypass drug resistance mechanisms in the membranes of a cultured leukemia cell line and release enough therapeutic drug to kill the cancer cell.

Caltech celebrates ten years of Scaffolded DNA Origami

By | 2018-01-25T13:09:20-07:00 March 14th, 2016|Bionanotechnology, Foresight Kudos, Found On Web, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology|

California Institute of Technology is holding a symposium to honor Paul Rothemund's seminal contribution to the field of DNA nanotechnology: the research paths opened by the technology, and where they might lead.

Crowd-sourced RNA structure design uncovers new insights

By | 2017-06-01T14:01:38-07:00 March 12th, 2016|Bionanotechnology, Computational nanotechnology, Machine Intelligence, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Research|

Thousands of amateurs playing the online RNA folding game Eterna, backed up by a real-world automated lab testing their predictions, have provided insights to improve the algorithms computers use to design RNA molecules.

Tightly-fitted DNA parts form dynamic nanomachine

By | 2017-06-01T14:01:39-07:00 March 10th, 2016|Artificial Molecular Machines, Atomically Precise Manufacturing (APM), Bionanotechnology, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanotech, Nanotechnology, Productive Nanosystems, Research|

A rotor with DNA origami parts held together by an engineered tight fit instead of by covalent bonds can revolve freely, driven by Brownian motion and dwelling at engineered docking sites.

DNA nanotechnology provides new ways to arrange nanoparticles into crystal lattices

By | 2017-06-01T14:01:39-07:00 February 19th, 2016|Bionanotechnology, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanoscale Bulk Technologies, Nanotech, Nanotechnology, Research|

Two research teams present two different methods for using single strands of DNA to link various nanoparticles into complex 3D arrays: one using DNA hairpins for dynamic reconfiguration and the other using a DNA origami scaffold.