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        Lipid coat protects DNA nanorobot from immune attack

        Enveloped DNA nanostructures were developed to escape attacks from nucleases and the immune system, opening a path to ever more sophisticated DNA nanomedical devices.

        Robust triangular RNA brick adds to RNA nanotechnology toolkit

        The complex molecular recognition code of RNA offers RNA nanotechnology a greater variety of 3D structures and functions than are present in DNA nanotechnology, but the RNA structures can be fragile. New RNA triangles that resist boiling solve this problem.

        DNA nanotechnology replicates enzyme cascade

        A swinging DNA arm added to a DNA scaffold makes it possible for two enzymes attached to the scaffold to complete a coupled chemical reaction.

        A bird’s-eye view of half a century of nanotechnology

        Reviewing Eric Drexler’s Radical Abundance, Phil Bowermaster provides an informed and insightful overview of the controversies that greeted the proposal for a nanotechnology aimed at developing a practical technology for atomically precise manufacturing. Along the way he shows how Drexler’s outlook evolved from 1986 to 2013.

        US government report highlights flaws in US nanotechnology effort

        The concern of the US GAO for a gap in nanomanufacturing is well-placed, but it is only half of the problem with the limited US vision of the impact of nanotechnology on the future world economy.

        Integrating DNA nanotechnology and RNA to transport nanoparticles along nanotubes

        A possible forerunner to a future molecular assembly line uses an artificial DNA motor to transport an artificial nanoparticle along a carbon nanotube track.

        Upcoming Book Explores Nanomedical Device and Systems Design

        A new book by Frank Boehm explores the challenges, possibilities, and visions of nanomedical device and systems design.

        Computational design of protein-small molecule interactions

        A major advance in the computational design of proteins that bind tightly to specific small molecules will facilitate several technologies, possibly including the development of atomically precise manufacturing.

        Molecular sponges give atomic structures of trace substances

        A porous metal-organic framework ‘host’ soaks up molecular ‘guests’ to form a crystalline complex, the structure of which can be determined by X-ray crystallography, providing atomic-resolution structures of minute amounts of guest molecules, and perhaps eventually other nanostructures.

        Recent highlights and discussions of APM concepts

        The release of Eric Drexler’s new book Radical Abundance has sparked a resurgence of discussion about nanotechnology and the global future. Last month, Nanowerk reprinted Drexler’s blog write-up entitled The Physical Basis of High-Throughput Atomically Precise Manufacturing, a reader-friendly overview highlighting parallels between molecular manufacturing and conventional chemistry and manufacturing. Over the last couple months,… Continue reading Recent highlights and discussions of APM concepts

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