Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.
Adding more chemical interactions to DNA nanotechnology
![](https://foresight.org/wp-content/uploads/2022/11/edwardson_sleiman_dnacages-1.png)
Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.
A pillar constructed and positioned using DNA nanotechnology holds two gold nanoparticles and a dye molecule to enhance fluorescence over a hundred fold.
Two open access reviews portray the widening approach of DNA nanotechnology toward more complex atomically precise systems.
A simple DNA scaffold organizes light-collecting molecules for artificial photosynthesis.
Biotechnology-based isolation and amplification of sequence-verified clones of DNA oligonucleotides will provide longer and less expensive materials for building complex DNA nanostructures and nanomachinery.
By forcing the geometry of the junctions upon which DNA nanotechnology depends, researchers have increased the collection of 2D and 3D structures that they can build to include wire frames and mesh structures.
Functioning DNA nanorobots to deliver specific molecular signals to cells were designed by combining DNA origami, DNA aptamers, and DNA logic gates.
Tiles made from DNA helices have been made to self-assemble into a more complex structure, which then was used to seed the formation of a complementary structure. This second structure in turn seeded the formation of multiple copies of the first structure.
DNA nanotechnology provides cell-surface sensors for real-time monitoring of single cells, including potential use in personalized medicine to test which drugs would be suitable for which individuals.
The capabilities of scaffolded DNA origami procedures have been expanded to construct arbitrary, two- and three-dimensional shapes.