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Adding more chemical interactions to DNA nanotechnology

Modifying DNA strands with lipid-like molecules opens more possibilities for designing DNA structures for drug delivery and other purposes.

DNA nanotechnology positions components to optimize single-molecule fluorescence

A pillar constructed and positioned using DNA nanotechnology holds two gold nanoparticles and a dye molecule to enhance fluorescence over a hundred fold.

Reviews of DNA nanotechnology-atomically precise microscale objects

Two open access reviews portray the widening approach of DNA nanotechnology toward more complex atomically precise systems.

DNA nanotechnology builds solar energy antenna

A simple DNA scaffold organizes light-collecting molecules for artificial photosynthesis.

Mass production of higher quality oligonucleotides to spur DNA nanotechnology

Biotechnology-based isolation and amplification of sequence-verified clones of DNA oligonucleotides will provide longer and less expensive materials for building complex DNA nanostructures and nanomachinery.

Re-engineering a junction to give a new twist to DNA nanotechnology

By forcing the geometry of the junctions upon which DNA nanotechnology depends, researchers have increased the collection of 2D and 3D structures that they can build to include wire frames and mesh structures.

DNA nanotechnology-based nanorobot delivers cell suicide message to cancer cells

Functioning DNA nanorobots to deliver specific molecular signals to cells were designed by combining DNA origami, DNA aptamers, and DNA logic gates.

Self-replication achieved using structural DNA nanotechnology

Tiles made from DNA helices have been made to self-assemble into a more complex structure, which then was used to seed the formation of a complementary structure. This second structure in turn seeded the formation of multiple copies of the first structure.

DNA nanotechnology provides detailed monitoring of single cells

DNA nanotechnology provides cell-surface sensors for real-time monitoring of single cells, including potential use in personalized medicine to test which drugs would be suitable for which individuals.

DNA nanotechnology builds 3D forms with complex curves (includes video)

The capabilities of scaffolded DNA origami procedures have been expanded to construct arbitrary, two- and three-dimensional shapes.

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