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Gaming the Future: The Book!

Results for ""protein design""

We found 56 results for your search.

Large, open protein cages designed and built

Design principles have been developed and tested to construct novel synthetic protein monomers that can self-assemble into large, open protein cages for potential use in vaccines and drug delivery.

Broadening the synthetic biology path to molecular nanotechnology

Advances in the de novo design of coiled-coil proteins made by two different research groups proceeding by two different routes demonstrate that the range of protein nanostructures potentially available for various molecular machine systems is significantly larger than the range of such structures already exploited by natural selection.

To fight inflammation nanoparticles turn ‘naughty’ neutrophils into ‘nice’ neutrophils

By targeting the protein that attaches a type of immune cell called neutrophils to blood vessel walls where they cause serious tissues damage, the neutrophils are released and returned to the circulation to resume their normal functions.

Will crowdsourced RNA designs advance nanotechnology?

A very large community of online gamers has consistently produced RNA designs that outperform the best design algorithms by a large margin. Can online gamers designing RNA, protein, and other molecules contribute to the development of atomically precise manufacturing?

Computational design of protein-small molecule interactions

A major advance in the computational design of proteins that bind tightly to specific small molecules will facilitate several technologies, possibly including the development of atomically precise manufacturing.

Molecular sponges give atomic structures of trace substances

A porous metal-organic framework ‘host’ soaks up molecular ‘guests’ to form a crystalline complex, the structure of which can be determined by X-ray crystallography, providing atomic-resolution structures of minute amounts of guest molecules, and perhaps eventually other nanostructures.

Nanotechnology milestone: general method for designing stable proteins

Five proteins were designed from scratch and found to fold into stable proteins as designed, proving the ability to provide ideal, robust building blocks for artificial protein structures.

New method to identify intermediates in protein folding

Tryptophan residues introduced at various positions in a protein chain identify folding intermediates that are too short-lived to be structurally characterized otherwise.

Gamers, citizen science, and protein structures (Video link)

The Foldit approach to protein structure determination and protein design has proved its worth with the solution by citizen scientists in three weeks of an important protein structure that had stumped scientists working on the problem for more than a decade.

Designing protein-protein interactions for advanced nanotechnology

Progress in computational modeling of protein structures and in designing protein interfaces that bind in a desired geometrical orientation prepare the way for designing protein components of molecular machine systems.

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