Presenters
Ravi Pandya is a Principal Software Architect at Microsoft Research. He had a startup called Hyperchem which dealt with molecular mechanics and gave him his start in nanotechnology. He presented to Xanadu, where he met with Eric Drexler. Ravi started moving into genomics and biotech, and is currently working on an antigen map….
Tad Hogg is an Institute of Molecular Manufacturing Research Fellow, and was a Member of the Research Staff at Hewlett-Packard Laboratories and the Xerox Palo Alto Research Center (PARC). Tad holds a PhD from Stanford and BS from Caltech, both in physics…
Molecular Machines: Computing
Key Takeaways – Ravi:
- T-cells bind to HLA (Human Leucocyte Antigen) molecules to identify pathogens in the body
- T-Cell receptors determine specificity for binding
- Ravi is mapping the potential TCR conformations using machine learning
- This should help uncover hidden immunotherapy ideas
Key Takeaways – Tad:
- There are three areas for molecular machines – discovery, control of individual machines, and design behavior for large numbers of machines
- Discovery entails using simulations to visualize machines we cannot yet build, and to use machine learning to design and fabricate conceptual machines
- We have poor intuition for molecular machines with regard to thermal motion and viscous damping
- Inertial motion has different rest states than viscous motion
- Swarm behavior is the ideal design philosophy for robots which are numerous but have limited programming capacity
