Multi Omics Clock Foundation
With Jason Mercurio
What is the most undervalued area for longevity progress we should pursue?The relationships between biomarkers are incredibly undervalued. Mapping biomarkers to disease pathways, having quantifiable endpoints for therapeutic studies, and increasing cross collaboration would improve the success probabilities for longevity drugs.Where are we today? Where would we like to be?Today there are lots of small trials, not necessarily well designed, using single biomarkers. Changing biomarkers have not been tied to patient outcomes. In the long term we would like to see reversing aging clocks leading to measurable improvements in health.What public and private actions have the biggest impact on those goals?Collecting blood and banking it in intervention studies, measuring as many clocks as possible, standardization, and forming a biobanking are all high impact steps.What people, funding, resources, experiments would be required to test this hypothesis?Creating a competition to reverse measurable biological age using lifestyle, health, and cognitive biomarkers. Supporting organizations such as OpenCures, VitaDAO, and CureDAO to generate biobanking, funding, and data sharing respectively. We can generate open collaboration via a Clock Summit to create commitments and standardization within the field.