Engage / Grants / AI for Science & Safety Nodes

AI for Science & Safety Nodes

Funding, compute, and office space in San Francisco and Berlin.

Physical hubs for AI-powered science and safety

Our two hubs in San Francisco and Berlin offer project funding, office and community spaces, and local compute for ambitious researchers and builders with an AI-first approach to advance science and safety.

Ecosystem for decentralized, AI-driven progress

Artificial intelligence is accelerating the pace of discovery across science and technology. But today’s AI ecosystem risks centralizing compute, talent, and decision-making power – concentrating capabilities in ways that could undermine both innovation and safety.

To counter this development, we are building a decentralized network of Nodes dedicated to AI-powered science and safety. The goal is to empower researchers and builders with a mission-aligned ecosystem, where AI-driven progress remains open, secure, and aligned with human flourishing.

Our Nodes offer

Apply for all three types of support, or select one or two based on your needs. Please note: we prioritize AI-first projects that want to be active, in-person members of one of our hubs. The value of the Nodes comes from peer collaboration and the work that happens between scheduled programming. Funding-only applications are considered only in exceptional cases.

Follow our Foresight calendar for our local AI Node events.

Update to Our Grants

Our grants are shifting to focused RFPs. We’re moving from open, general applications to targeted calls on specific bottleneck problems in AI safety and AI-first science. Fewer, sharper questions, backed by more meaningful funding.

Until the RFPs are published we are not accepting further submissions. Full details, including focus areas and how to apply will be up shortly. Stay tuned.

The rest of this page outlines what kind of projects we are excited to support and the terms for our grants.

AI-first projects

To keep up with and leverage increasing AI capabilities, we give priority to projects that use AI as the primary engine for progress across our focus areas. That means your project involves using AI to achieve X. The goal is to enable science and safety to accelerate in tandem with AI – for the safe and beneficial evolution of intelligence.

Focus Areas

We are excited to fund and support work in the following areas.

1. AI for Security 

Traditional security paradigms, often reactive, piecemeal and human-driven, cannot scale to match the speed, scale, and complexity of AI-supported attacks. We seek to support self-improving defense systems where AI autonomously identifies vulnerabilities, generates formal proofs, red-teams, and strengthens the world’s digital infrastructure.

2. Private AI

To ensure that AI progress occurs openly without sacrificing privacy, we want to support work that applies AI to enhance confidential compute environments, scale privacy mechanisms for handling data, and design infrastructure that distributes trust. This includes projects building a local, private compute stack and AI setup.

3. Decentralized & Cooperative AI

We fund work that builds decentralized intelligence ecosystems – where AI systems can cooperate, negotiate, and align – so societies remain resilient in a multipolar world. We are especially interested in projects that enable peaceful human–AI co-existence and create new AI-enabled mechanisms for cooperation.

4. AI for Science & Epistemics

In addition to applying AI to specific problems, we need better platforms, tools and data infrastructure to accelerate AI-guided scientific progress generally. Similarly, to get our sense-making ready for rapid change, we are interested in funding work that applies AI to improve forecasting and general epistemic preparedness.

5. AI for Neuro, Brain-Computer Interfaces & Whole Brain Emulation

We are interested in work that uses frontier models to map, simulate, and understand biological intelligence – building the foundations for hybrids between human and artificial cognition, from brain-computer interfaces to whole brain emulation. We care about this domain specifically for its potential to improve humanity’s defensive position as AI advances.

6. AI for Longevity Biotechnology

We want to fund work that applies AI to make progress on scientific frontiers in longevity biotechnology – from biostasis and replacement, to gene therapy and exosomes.

7. AI for Molecular Nanotechnology

We support work that uses AI to make progress on scientific frontiers in molecular nanotechnology – from design and simulation, to construction and assembly of nanomachines.

Grants connected to the hubs

FAQ

How much funding can be requested? 

We award around $3M in total funding annually. Grants typically range from $10,000 to $100,000, with higher amounts being awarded to the AI safety-oriented focus areas, and smaller to longevity biotech and molecular nanotech projects.

What is required of applicants? 

To create community among mission-aligned projects, we strongly prefer applicants who plan to use the nodes in San Francisco or Berlin. We will accept “funding-only” projects only in exceptional cases.

What are the application deadlines? 

We are updating our grants process. Full details, including application deadlines will be up shortly. Stay tuned.

How do I apply?

By completing this application form – also linked at the top of this page.

What is the review process? 

The approximate review time is two months after each application deadline. You can request fast processing, but we may not be able to honor it. Review time for smaller funding amounts may be faster.

Proposals are first reviewed in-house for fit and quality. Strong submissions are sent to technical advisors for further evaluation. If your proposal advances, we may follow up with written questions or a short call. Unfortunately, due to the number of applications we receive, we are unable to provide individual feedback to unsuccessful applicants.

Who can apply?

We accept applications from individuals, teams, and organizations. Both non-profit and for-profit organizations are welcome to apply, but for-profits should be prepared to motivate why they need grant funding.

What are the evaluation criteria? 

Please note that the AI safety criteria do not apply to the AI for longevity biotechnology and molecular nanotechnology focus areas.

What are the funding terms? 

Launch your own AI Node

Our long-term vision is a global, decentralized network of AI Nodes dedicated to the use of AI to further science and human safety. We’re starting with our own hubs in San Francisco and Berlin, but are also interested in collaborating to set up independent Nodes led by others elsewhere.

We’re envisioning each Node serving as its region’s independent hub: equipped with local compute infrastructure to support a community of researchers and builders advancing secure, safe, private cooperative AI and AI for science. Nodes in the network could share compute, talent, and progress, where aligned, while retaining their own character and governance: forming a meaningful alternative to centralized AI development. 

For the right teams, we can offer limited incubation support such as compute know-how, smaller seed funding, plus integration into our wider network.

Are you already building an AI Node, or interested in establishing one in your area? Fill out the form below as an expression of interest to start a conversation.

Further questions or feedback?

Please contact us at [email protected]

Grantees

Node
Category
Year

Yue Zhao

Souti Chattopadhyay

Quintus Kilbourn

Sudo ML

Joel Shor

Jesse Posner

Previously funded

Ed Boyden

Boyden Lab

Dawn Song

University of California

Dan Hendrycks

Center for AI Safety

Ariel Procaccia

Harvard University

Blake Richards

Mila

Gernot Heiser

UNSW Sydney

Mark Miller

Agoric

Florian Tramer

ETH Zurich

Adam Gleave

FAR AI

OpenMined

Konrad Kording

Kording Lab

Georgios Kaissis

Hasso Plattner Institute, University of Potsdam

Mayank Varia

Center for Reliable Information Systems & Cyber Security (RISCS), Boston University

Dean Thomas

The Cronin Group, University of Glasgow

Chiara Herzog

King's College London

Talmo Pereira

Salk Institute for Biological Studies

Eva Dyer

University of Pennsylvania

Mark Hamalainen

Longevity Biotech Fellowship (LBF)

Benjamin Wilson

Metaculus

MATS Research

Herbie Bradley

University of Cambridge

Fazl Barez

University of Oxford

Lisa Thiergart

Security Level 5 Task Force

Nora Ammann

PIBBSS

Adam Binksmith

AI Digest (Sage)

Naomi Brockwell

Ludlow Institute

Yevgeniy Vorobeychik

Washington University in St. Louis

Andrew Payne

E11 Bio

Yue Zhao

University of Southern California (USC), FORTIS Lab

Christian Schroeder de Witt

University of Oxford

Funders

This program is supported by private funders as well as Protocol Labs, Gigafund, and 100 Plus Capital.

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