Autonomous and Surgery-free Nano-Electronics for Brain-Computer Symbiosis

Over three billion people worldwide suffer from neurological disorders, yet current treatments remain limited by the inability to access the brain safely and precisely. In this talk, Sarkar will introduce Circulatronics—a new paradigm in bioelectronics that enables autonomous, non-surgical electronic implants capable of self-implantation in target regions and precise neuromodulation using wireless electromagnetic fields.

Unlike conventional implants that require invasive surgery and bulky hardware, these sub-cellular nanoelectronic devices can be introduced into the body and seamlessly integrate with biological tissue, opening a path toward treating previously intractable conditions. I will present our preclinical results demonstrating targeted self-implantation, high precision treatments, and strong safety profiles, as well as our roadmap toward clinical translation.

Finally, Sarkar will discuss how this platform can redefine not only the treatment of diseases such as brain cancer, and diseases of aging and blindness, but also the future of brain–computer symbiosis—where AI powered electronics and biology operate together at the cellular scale. This work represents a shift from invasive implants to a scalable, accessible, and transformative approach to medicine.

https://www.nature.com/articles/s41587-025-02809-3