Replacement Technology for Radical Life Extension

Aging is modifiable through small molecules and gene therapies, yet both approaches face significant limitations. Small molecules can reach widespread areas of the body but often have limited efficacy and unintended side effects. Gene therapies, while precise and powerful, currently lack the means for reliable, systemic application in adults. These challenges hinder their potential to substantially extend human lifespan. A promising alternative is the replacement of damaged or diseased tissues and organs with healthy substitutes. This strategy bypasses the complexities of targeting individual aging pathways, as demonstrated in modern transplantation practices: when a liver disease cannot be cured, a new liver can restore health. This seminar explores current replacement therapies, emerging technologies under development, and their potential to revolutionize the treatment of aging and transform medicine in the near future.