Presenter
Alexandra Stolzing, Prof. of Biogerontological Engineering at Loughborough University
Professor of Biogerontological Engineering Deputy Associate Dean (Enterprise) University Genetically Modified Organisms Officer. Research Interests: - stem cell aging & stem cell function in aging - interface of immunology and stem cell function - cellular pathology in age-related neurodegeneration & Alzheimer’s Disease - improving cryopreservation of cells & tissues - inducing pluripotency & partial reprogramming - improving stem cell function in vivo automated systems for cell & tissue production - quality control assays for aged cells delivery tools for cell-based therapies
Summary:
Alexandra Stolzing, Prof. of Biogerontological Engineering at Loughborough University, asks this question – can the community come together to define minimal criteria for defining a senescent cell? Senescent cells are cells which are incapable of division, effectively reaching the end of their regenerative potential. The scientific definition of senescence is still ambiguous, and this is causing problems for identification and therapeutics against senescent cells. She asked for recommendations to set standards for experimental protocol and brought attention to the need for an aging model data hub. She also reiterated the need for shorter lifespan studies that use proxy measurements to determine longevity success.
