Programmable Blood Clotting

What are you trying to do?We want to build a system for external control of local activation and deactivation of blood clotting using magnetic fields.How is it done today?The current solution is to systemically administer blood thinners, which leads to bleeding and buildup of resistance. There are also physical ‘temporary tourniquet’ options.What is new in your approach?Using nanobots to actuate blood coagulation based on magnetic fields is absolutely not being done by anyone else. The novel features are reversability and precise control.If you are successful, what difference will it make?The immediate impact is in the emergency room; for stroke, embolism, covid patient, and premature babies survival. It could prevent >1M deaths annually in the US.Cost and timeline?$1M and 2 years for in vitro proof-of-concept, 5 years + $$ for in vivo animal model.What are the mid-term and final exams to check for completeness?The milestones of progress can be measured by demonstration in-vitro, in drawn blood, in mice, in pigs, and finally in humans.