Gaming the Future: The Book!

Biotech & Health Extension

sponsored by 100 Plus Capital

A group of scientists, entrepreneurs, funders, and institutional allies who cooperate to advance biotechnology to reverse aging, extend human healthspans, and improve cognition. Meetings are private and may be off the record. Recorded seminars are below.

Upcoming seminars

April 25, 2023

Moving beyond chronological age based biological clocks: the problems and recent solutions for DNA methylation clocks

With Varun Dwaraka

May 17, 2023

Foresight Biotech Group

With Owen Phillips, BrainKey

June 14, 2023

A Moonshot to Move the 13 Mitochondrial Genes to the Human Nucleus

With Mariёlle van Kooten, Stanford University

October 11, 2023

Foresight Biotech Group

With Sofya Lebedeva

SEMINAR SUMMARIES

Alexander Fedintsev | How Old Matrix Kills Us

Award Ceremony | The Hypothesis Longevity Prize

Yuri Deigin | Epigenetic Rejuvenation by In Vivo Partial Reprogramming: Past, Present, and Future

Foresight Mentorship with Jaan Tallinn

Ana Maria Cuervo | Targeting Selective Autophagy in Aging and Age-related Diseases

V. Gladyshev, M. Moqri, V.Sebastiano | Quantifying Aging

Reason, Fight Aging | Towards Biotechnology to Finally Defeat Cholesterol

Joao Pedro de Magalhaes | The Scientific Quest for Immortality

Bryan Johnson | Blueprint Rejuvenation Athlete

Matt Kaeberlein | Companion Animals in Geroscience: Challenges and Opportunities

Career Counseling with Sonia Arrison

Diana Guallar | Epitranscriptomics as Novel Players in Aging and Rejuvenation

Tony Wyss-Coray | Young Blood for Old Brains

Collin Ewald | Aging & The Extracellular Matrix

Justin Sonnenburg | The Gut Microbiome is a Key Lever on Human Health

George Church | Gene & Cell Therapies for Age-related & Infectious Diseases

Emil Kendziorra, Max More | Cryonics Sign-Up Q&A + Demo

DeSci Boston 2022 | Foresight Tech Trees

Tom Bell & Kalon Boston | In Search of the Best Policies for Translational Geroscience

Jennifer Garrison, Buck Institute | Reframing Health and Aging through the Lens of Reproduct

Tom Kalil | Foresight Fellows Career Counseling

Vera Gorbunova | Mechanisms of longevity Lessons from Long-Lived Mammals

Emil Kendziorra, Max More | Cryonics Sign-Up Q&A + Demo

Suresh Rattan | Hormesis for Healthy Aging and Longevity

David Rubinsztein, Cambridge | Autophagy and Neurodegeneration

M. Reeves, Dr. S. Manson-Brown, C. Von Boeselager, N. Lauc | Women’s Health and Longevity

Michael Fossel | Aging: Understanding it, Reversing it

Sonia Arrison, 100 Plus Capital | Investor Q&A

Dylan Livingston, Alliance for Longevity Initiatives | Policy Focus

Clarice D. Aiello | From Nanotech To Living Sensors

Dylan Livingston, Alliance for Longevity Initiatives & Joe DeSantis | Policy Focus

Christian Angermayer, Rejuveron | Longevity & Deep Tech Investor Q&A

Vittorio Sebastiano | Epigenetic Reprogramming of Aging

Dylan Livingston, Alliance for Longevity Initiatives | Longevity Policy Opportunities

2022 Group Launch | Your Biotech Goals

Karl Pfleger, Agingbiotech.info | Longevity Investor Q&A

Progress on Health Extension in 2021 with Sonia Arrison, 100 Plus Capital

Reason, Fight Aging | Q&A on How to Fight Aging

Sergey Young, Longevity Vision Fund | Neil Littman, Bioverge | Longevity Investing

Kristen Fortney, Bioage | Building a pipeline of clinical-stage therapies to target aging

David Furman, Buck Inst. | Systems Immunology of Aging to Enable Precision Preventative Medicine

Atherosclerosis: The As Yet Undefeated Monster

Emil Kendziorra & Aschwin De Wolf | Biostasis & Cryonics Q&A

Alexander Fedintsev | Biohacking – A Necessary Component of a Strategy for Radical Life Extension

Daniel Belsky, Terrie Moffitt | The DunedinPoAm DNA Methylation Algorithm

Michael Snyder, Stanford University | Monitoring Personal Health and Ageotypes Using Big Data

Bioelectric Networks: Taming the Collective Intelligence of Cells for Regenerative Medicine

Drug Target Discovery for Cellular Rejuvenation by ‘Driver’ Clocks | Daniel Ives, Shift Bioscience

TAME Q&A: Lessons for Progress on Aging | Nir Barzilai, Albert Einstein School of Medicine

”Patient Trials in a Dish” Paths Forward | David Gobel, Methuselah, Keith Murphy, Organovo

Biomarker Standardization | Morgan Levine, Yale, Jamie Justice, Wake Forest School of Medicine

EpigeneticClocks: What’s New & What’s Missing? | Steve Horvath, UCLA

Biomarker & Aging Clock Development | Vadim Gladyshev, Harvard, Gordan Lauc, GlycanAge

Longevity as a Service: AI & Aging Clocks | Alex Zhavoronkov, Deep Longevity & Insilico Medicine

Dylan Livingston | ALARMA (America’s Longevity, Aging and Regenerative Medicine Association)

Greg Fahy, Intervene Immune | Thymus Rejuvenation Progress Update

Biomarkers and Drug Development: Regulatory Perspective | Christopher Leptak

James Peyer | Cambrian Bio: How to Fund and Build Geroprotectors

Promising Aging Approaches from an NIA Perspective | Ronald Kohanski, National Institute on Aging

Clinical Trials & Senolytics | Dr. James Kirkland, Mayo Clinic

Brain Cell Replacement to Beat Aging | Jean M. Hebert, Albert Einstein School of Medicine

Academic blindspots | B. Kennedy, Buck Institute, J. Deelen, Max Planck Institute, L Cox, Oxford Uni

Tissue Rejuvenation via Plasma Dilution | Irina Conboy, UC Berkeley

Aging industry blindspots | S Arrison, 100 Plus Capital, K Pfleger, AgingBiotech.info, M West, AgeX

Biotech & Health Extension: 2021 Goals & Opportunities | Your Input Desired

Regulatory Steps and Hurdles in Clinical Studies of Aging Int.| Dr. James Kirkland, Mayo Clinic

TAME & Biomarker Q&A with Nir Barzilai, Institute for Aging Research

Aging Ecosystem Multipliers & Focused Research Orgs. | Adam Marblestone, Schmidt Futures Fellow

Underlying Features of Epigenetic Aging Clocks | Morgan Levine, Yale University

Q&A with former US Food and Drugs Commissioner | Robert Califf, Verily

OneSkin Progress Report | Carolina Reis, CEO Oneskin

Progress Updates: Methuselah Fund, Apollo VC, Repair Bio, Vitamin D & COVID-19

Accelerating Anti COVID 19 Drug Platforms Relevant for Aging | Alpha Lee, Postera

Diabetes, Healthspan & Gene Therapy | Anthony Di Franco, Open Insulin, Liz Parrish, BioViva

Health Extension Biohacking: Diet, Supplements, Lifestyle | Creon Levit, John Furber

Biohacking COVID-19 & Beyond | Steve Fowkes, Amy Proal

Advancing Immunosenescence Therapies | Sarah Constantin, Greg Fahy

Genetic Variation, Aging & Relationship to COVID-19| Joris Deelen, Albert Ying

Genetics, Aging & COVID 19 | Victor Bustos, Apollo VC

Health Commons | Kevin Perrott, Hong Jiang, Brian Delaney, Keith Comito, Steve Fowkes

Aging Policy: Lessons from Singapore | Brian Kennedy, Shazib Pervaiz, Swaine Chen, Louis Hawthorne

Aging & COVID-19: Policy & Strategy | Aubrey de Grey, Jim O’Neill, Bernard Siegel

Glycans, Aging & COVID-19

Reverse-Engineering the Genomic Causes of Disease

Andre Watson, Ligandal: An Ultra-fast Vaccine Approach for Global Biodefense

Longevity Investment: Aubrey de Grey, Karl Pfleger, Sonia Arrison, Nils Regge, Joe Betts-Lacroix

Maddalena Adorno, Dorian Therapeutics: New Therapeutics to Block Cellular Senescence

John Lewis, Inflection Point Bio: A Programmable Platform for Selectively Killing Cells

Francisco LePort, Gordian Biotechnology: Improving Drug Development Via In Vivo Screening

Hong Jiang, ElonLife : Practicing Anti-Aging

Eli Mohamad, X-Therma: Recent Breakthroughs for Ending the Organ Transplant Waitlist

Ellen Heber-Katz | Methuselah Rising: Materials for Regeneration and Longevity | VISION WEEKEND 2019

Zinaida Good | Reversing Epigenetic Aging and Immunosenescent Trends in Humans | VISION WEEKEND 2019

Aubrey de Grey | Reaching Escape Velocity in Longevity for Most Alive Today | VISION WEEKEND 2019

Biotech Investing in Longevity: Aubrey de Grey, Gordon Lithgow, Mike West

Forever Labs – Mark Katakowski @Biotech Investing in Longevity

Biotech Investing in Longevity Panel 1: Mark Katakowski, Sonia Arrison, Sarah Constantin

Methuselah Fund, Leucadia Therapeutics, Turn Biotechnologies & Repair Biotechnologies

Longevity Myth Busting – Aubrey de Grey