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        Gaming the Future: The Book!

        Nanotech

        Workshop

        Molecular Systems Design

        Hosted by

        September 11 - 12,
        2023, 9 am - 5 pm

        Hosted by

        Adam Marblestone

        Convergent Research

        Benjamin Reinhardt

        Speculative Technologies

        Allison Duettmann

        Foresight Institute

        The Institute, Salesforce Tower, San Francisco

        Apply for a Subsidized Ticket

        Buy Tickets NOW !

        Apply to join

        Become a Sponsor

        Goal

        Complex molecular machines system design could be sped up by integrating emerging approaches and advancements on the software and simulation-side. Some areas were highlighted by ourĀ 2022 workshop, some are entirely new. This two-day event invites leading researchers, entrepreneurs, and funders to put the pieces together and drive progress towards the original vision of nanotechnology:Ā creating reprogrammable tools that can create individually specified chemical bonds at scale. Explore new opportunities, form lasting collaborations, and join us in cooperating on shared long-term goals of the Molecular Machines space.

        Format

        An intro session on potential architectures for advanced molecular machine tools that could be created with current technology is followed by rapid keynotes discussing relevant approaches and design frameworks in-depth.Ā Working groups will refine promising architectures, determine the work required to make progress on the needed systems, andĀ what the first potential use-cases could be.Ā Agenda below. Apply to join as attendee, sponsor, or presenter.

        What to expect

        To get a feeling of what to expect, please review our 2022 workshop.

        Workshop Video Summaries

        Allison Duettmann | Introduction @ Molecular Systems Design Workshop 2023

        Benjamin Reinhardt | Workshop Intro presentations @ MSD Workshop 2023

        Adam Marblestone | Molecular 3D Printing Architectures @ Molecular Systems Design Workshop 2023

        Alexis Courbet | Computational Design of Self Assembling Protein Nanomachines @ MSD Workshop 2023

        Carlos E. Castro | Programming Mechanical Function of DNA Origami @ MSD Workshop 2023

        Chris Schafmeister | CANDO & Programmable Spiroligomers @ Molecular Systems Design Workshop 2023

        William Shih | Self Assembling DNA Nanostructures @ Molecular Systems Design Workshop 2023

        Julian Englert | Making a Protein Printer That Turns Bits Into Molecules @ MSD Workshop 2023

        Fei Zhang | Assembly and Reconfiguration in DNA Tile and Origami Systems @ MSD Workshop 2023

        Ruohong Shi | Programming Soft Material Shape Change Using DNA Polymerization @ MSD Workshop 2023

        Reza Moheimani | MEMS STM Platform @ Molecular Systems Design Workshop 2023

        Philip Moriarty | Adding a Dimension to Atom-by-Atom Assembly @ MSD Workshop 2023

        Adam Braunschweig | The Surface Chemistry Bottleneck @ Molecular Systems Design Workshop 2023

        James Seale | Placing Molecular Pumps on Polymeric Micelles @ Molecular Systems Design Workshop 2023

        Hein-Pieter van Braam | User friendly Molecular System Design @ MSD Workshop 2023

        Petr Å ulc | Multiscale Modeling for Nanostructure Design @ Molecular Systems Design Workshop 2023

        Stephane Redon | SAMSON Computational Nanoscience Updated @ Molecular Systems Design Workshop 2023

        Boris Fain | Quantum Accuracy at Human Speed @ Molecular Systems Design Workshop 2023

        Lilian Chong | Protein Binding Simulations with Pathways and Kinetics @ MSD Workshop 2023

        Workshop Presentation Group 1 | A Molecular ā€œPrinterā€ @ Molecular Systems Design Workshop 2023

        Workshop Presentation Group 2 | A Molecular ā€œbreadboardā€ @ Molecular Systems Design Workshop 2023

        Workshop Presentation Group 3 | Molecular Legos @ Molecular Systems Design Workshop 2023

        Workshop Presentation Group 4 | Scanning-Tunneling Microscope / Atomic Force Microscope Assembly

        Workshop Presentation Group 5A | MATE-C Metaprotein Assembly for Therapeutic Engineering

        Workshop Presentation Group 5B | Small Molecule Approach @ Molecular Systems Design Workshop 2023

        Confirmed Participants

        Abhishek Singharoy, Arizona State University

        Adam Braunschweig, CUNY Advanced Science Research Center

        The surface chemistry bottleneck

        Adam Marblestone, Convergent Research

        Alexis Courbet, Baker Lab

        Computational Design of Self-Assembling Protein Nanomachines

        Alia Abbas, Stealth

        Allison Duettmann, Foresight Institute

        Anastasia Ershova, Harvard University

        Aristeidis Symeonidis, Pfizer

        Ben Reinhardt, Speculative Technologies

        Boris Fain, Stanford University

        Quantum Accuracy at Human Speed

        Brenda Rubenstein, Brown University

        Carlos E Castro, Ohio State University

        Programming mechanical function of DNA origami

        Caleb Meredith, Chromatir

        Chris Schafmeister, Temple University

        CANDO & Programmable Spiroligomers

        Chris Wintersinger, Speculative Technologies

        David Forrest, Nexight Group

        Du Lin, UC Berkeley

        Erik Benson, Oxford

        Fei Zhang, Rutgers University

        Assembly and Reconfiguration in DNA Tile and Origami Systems

        Grigory Tikhomirov, UC Berkeley

        Haichao Wu, Harvard

        Hein-Pieter van Braam, Ramatak Inc

        User-fiendly Molecular System Design

        Iqbal Utama, Northwestern Univeristy

        Irene Regeni, Leiden University

        Jacob Majikes, National Institute of Standards and Technology

        James Gimzewski, UCLA Chemistry & Biochemistry Department

        James Seale, Northwestern Univeristy

        Placing Molecular Pumps on Polymeric Micelles

        John William (Bill) Efcavitch, Molecular Assemblies, Inc.

        Khalid Salaita, Salaita Lab

        Lillian Chong, University of Pittsburgh

        Protein Binding Simulations with Pathways and Kinetics

        Marco Ovalle, Groningen University

        Mark Friedenbach, Machine Phase Systems Inc.

        Maxime Ledent, University of Liege

        Michael Matthies, Arizona State University

        Niklas Rindtorff, LabDAO

        Niladri Mandal, Pennsylvania State University

        Pavi Dhiman, Prodigy Fellow

        Petr Sulc, Arizona State University

        Multiscale modeling for nanostructure design

        Philip Moriarty, Univeristy of Nottingham

        Adding a Dimension to Atom-by-Atom Assembly

        Reto Stamm, Root Applied Sciences

        Reza Moheimani, UT Dallas

        MEMS STM platform

        Ruohong Shi, Johns Hopkins University

        Programming Soft Material Shape Change Using DNA Polymerization

        Shucong Li, MIT

        Si-ping Han, Switch Therapeutics

        Stacy Copp, UC Irvine

        Stefan Borsley, Foresight Fellow, University of Manchester

        Stephane Redon, NANO-D

        SAMSON Computational Nanoscience Updated

        Stephen Fielden, University of Birmingham

        Tad Hogg, Institute for Molecular Manufacturing

        William Shih, Harvard University

        Self-assembling DNA Nanostructures

        Xinru Wang, Institute for Protein Design, University of Washington

        Yansong Ren, University of Manchester

        Yuanning Feng, Foresight Institute

        The Molecular Machines Tech Tree

        Zoe Ashbridge, University of Manchester

        Workshop

        Molecular Systems Design

        Become a Sponsor

        AGENDA

        Apply to join

        Sunday, Sept 9

        6.00 – 8.00 pm

        Speaker, Sponsor and Fellow drinks @Pebblebed VC HQ

        Monday, Sept 10

        09:00 ā€“ 10:00 am

        Arrival & Networking

        10:00 ā€“ 11:00 am

        Workshop Intro presentations

        • Allison Duettmann, Foresight Institute: Welcome & Format
        • Benjamin Reinhardt, Speculative Technologies &Ā  Adam Marblestone, Convergent Research: Molecular 3D Printing Architectures & Characteristics

        11:00 ā€“ 11:10 pm

        Break

        11:10 ā€“ 12:00 am

        Technologies Presentations

        • Alexis Courbet, Baker Lab Computational Design of Self-Assembling Protein Nanomachines
        • Carlos E Castro, Ohio State University: Programming mechanical function of DNA origami
        • Chris Schafmeister, Temple University: CANDO & Programmable Spiroligomers
        • William Shih, Harvard University: Self-assembling DNA Nanostructures
        • Julian Englert, Adaptyv Bio: Making a protein printer that turns bits into molecules

        12:00 ā€“ 01:00 pm

        Lunch (mentorship pairings)

        01:00 ā€“ 02:30 pm

        Other Systems ApproachesĀ  Presentations

        • Fei Zhang, Rutgers University: Assembly and Reconfiguration in DNA Tile and Origami Systems
        • Ruohong Shi, Johns Hopkins University: Programming Soft Material Shape Change Using DNA Polymerization
        • Reza Moheimani, UT Dallas:Ā  MEMS STM platform
        • Philip Moriarty, University of Nottingham: Adding a Dimension to Atom-by-Atom Assembly
        • Adam Braunschweig, CUNY Advanced Science Research Center: The surface Chemistry Bottleneck
        • James Seale, Northwestern University: Placing Molecular Pumps on Polymeric Micelles

        02:30 ā€“ 03:00 pm

        BreakĀ 

        03:00 ā€“ 04:00 pm

        Design Tools Presentations

        • Hein-Pieter van Braam, Ramatak Inc: User-friendly Molecular System Design
        • Petr Sulc, Arizona State University: Multiscale modeling for nanostructure design
        • Stephane Redon, NANO-D: SAMSON Computational Nanoscience Updated
        • Boris Fain, Stanford University: Quantum Accuracy at Human Speed
        • Lillian Chong, University of Pittsburgh: Protein binding simulations with pathways and kinetics

        Ā 

        04:00 ā€“ 04:30 pm

        Break

        04:30 ā€“ 05:30 pm

        Working group formationĀ 

        05:30 ā€“ 05:45 pm

        Closing presentationĀ 

        • Yuanning Feng, Foresight Institute: The Molecular Machines Tech Tree

        05:45 ā€“ 07:00 pm

        Dinner

        Tuesday, SeptemberĀ  11

        09:00 ā€“ 09:30 am

        Arrival & Networking

        09:30 ā€“ 12:30 pm

        Working groups on molecular machine architectures

        12:30 ā€“ 01:30 pm

        Lunch (mentorship pairings)

        01:30 ā€“ 03:30 pm

        Group presentations

        03:30 ā€“ 04:30 pm

        Meta challenge session & next steps

        04:30 ā€“ 06:00 pm

        Aftershow drinks & exploratory breakouts

        LOCATION

        The Institute
        San Francisco

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