Gaming the Future: The Book!

Nanotech

Workshop

Molecular Systems Design

Hosted by

September 11 - 12,
2023, 9 am - 5 pm

Hosted by

Adam Marblestone

Convergent Research

Benjamin Reinhardt

Speculative Technologies

Allison Duettmann

Foresight Institute

The Institute, Salesforce Tower, San Francisco

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Goal

Complex molecular machines system design could be sped up by integrating emerging approaches and advancements on the software and simulation-side. Some areas were highlighted by our 2022 workshop, some are entirely new. This two-day event invites leading researchers, entrepreneurs, and funders to put the pieces together and drive progress towards the original vision of nanotechnology: creating reprogrammable tools that can create individually specified chemical bonds at scale. Explore new opportunities, form lasting collaborations, and join us in cooperating on shared long-term goals of the Molecular Machines space.

Format

An intro session on potential architectures for advanced molecular machine tools that could be created with current technology is followed by rapid keynotes discussing relevant approaches and design frameworks in-depth. Working groups will refine promising architectures, determine the work required to make progress on the needed systems, and what the first potential use-cases could be. Agenda below. Apply to join as attendee, sponsor, or presenter.

What to expect

To get a feeling of what to expect, please review our 2022 workshop.

Confirmed Participants

Abhishek Singharoy, Arizona State University

Adam Braunschweig, CUNY Advanced Science Research Center

The surface chemistry bottleneck

Adam Marblestone, Convergent Research

Alexis Courbet, Baker Lab

Computational Design of Self-Assembling Protein Nanomachines

Alia Abbas, Stealth

Allison Duettmann, Foresight Institute

Anastasia Ershova, Harvard University

Aristeidis Symeonidis, Pfizer

Ben Reinhardt, Speculative Technologies

Boris Fain, Stanford University

Quantum Accuracy at Human Speed

Brenda Rubenstein, Brown University

Carlos E Castro, Ohio State University

Programming mechanical function of DNA origami

Caleb Meredith, Chromatir

Chris Schafmeister, Temple University

CANDO & Programmable Spiroligomers

Chris Wintersinger, Speculative Technologies

David Forrest, Nexight Group

Du Lin, UC Berkeley

Erik Benson, Oxford

Fei Zhang, Rutgers University

Assembly and Reconfiguration in DNA Tile and Origami Systems

Grigory Tikhomirov, UC Berkeley

Haichao Wu, Harvard

Hein-Pieter van Braam, Ramatak Inc

User-fiendly Molecular System Design

Iqbal Utama, Northwestern Univeristy

Irene Regeni, Leiden University

Jacob Majikes, National Institute of Standards and Technology

James Gimzewski, UCLA Chemistry & Biochemistry Department

James Seale, Northwestern Univeristy

Placing Molecular Pumps on Polymeric Micelles

John William (Bill) Efcavitch, Molecular Assemblies, Inc.

Khalid Salaita, Salaita Lab

Lillian Chong, University of Pittsburgh

Protein Binding Simulations with Pathways and Kinetics

Marco Ovalle, Groningen University

Mark Friedenbach, Machine Phase Systems Inc.

Maxime Ledent, University of Liege

Michael Matthies, Arizona State University

Niklas Rindtorff, LabDAO

Niladri Mandal, Pennsylvania State University

Pavi Dhiman, Prodigy Fellow

Petr Sulc, Arizona State University

Multiscale modeling for nanostructure design

Philip Moriarty, Univeristy of Nottingham

Adding a Dimension to Atom-by-Atom Assembly

Reto Stamm, Root Applied Sciences

Reza Moheimani, UT Dallas

MEMS STM platform

Ruohong Shi, Johns Hopkins University

Programming Soft Material Shape Change Using DNA Polymerization

Shucong Li, MIT

Si-ping Han, Switch Therapeutics

Stacy Copp, UC Irvine

Stefan Borsley, Foresight Fellow, University of Manchester

Stephane Redon, NANO-D

SAMSON Computational Nanoscience Updated

Stephen Fielden, University of Birmingham

Tad Hogg, Institute for Molecular Manufacturing

William Shih, Harvard University

Self-assembling DNA Nanostructures

Xinru Wang, Institute for Protein Design, University of Washington

Yansong Ren, University of Manchester

Yuanning Feng, Foresight Institute

The Molecular Machines Tech Tree

Zoe Ashbridge, University of Manchester

Workshop

Molecular Systems Design

Become a Sponsor

AGENDA

Apply to join

Sunday, Sept 9

6.00 – 8.00 pm

Speaker, Sponsor and Fellow drinks @Pebblebed VC HQ

Monday, Sept 10

09:00 – 10:00 am

Arrival & Networking

10:00 – 11:00 am

Workshop Intro presentations

  • Allison Duettmann, Foresight Institute: Welcome & Format
  • Benjamin Reinhardt, Speculative Technologies &  Adam Marblestone, Convergent Research: Molecular 3D Printing Architectures & Characteristics

11:00 – 11:10 pm

Break

11:10 – 12:00 am

Technologies Presentations

  • Alexis Courbet, Baker Lab Computational Design of Self-Assembling Protein Nanomachines
  • Carlos E Castro, Ohio State University: Programming mechanical function of DNA origami
  • Chris Schafmeister, Temple University: CANDO & Programmable Spiroligomers
  • William Shih, Harvard University: Self-assembling DNA Nanostructures
  • Julian Englert, Adaptyv Bio: Making a protein printer that turns bits into molecules

12:00 – 01:00 pm

Lunch (mentorship pairings)

01:00 – 02:30 pm

Other Systems Approaches  Presentations

  • Fei Zhang, Rutgers University: Assembly and Reconfiguration in DNA Tile and Origami Systems
  • Ruohong Shi, Johns Hopkins University: Programming Soft Material Shape Change Using DNA Polymerization
  • Reza Moheimani, UT Dallas:  MEMS STM platform
  • Philip Moriarty, University of Nottingham: Adding a Dimension to Atom-by-Atom Assembly
  • Adam Braunschweig, CUNY Advanced Science Research Center: The surface Chemistry Bottleneck
  • James Seale, Northwestern University: Placing Molecular Pumps on Polymeric Micelles

02:30 – 03:00 pm

Break 

03:00 – 04:00 pm

Design Tools Presentations

  • Hein-Pieter van Braam, Ramatak Inc: User-friendly Molecular System Design
  • Petr Sulc, Arizona State University: Multiscale modeling for nanostructure design
  • Stephane Redon, NANO-D: SAMSON Computational Nanoscience Updated
  • Boris Fain, Stanford University: Quantum Accuracy at Human Speed
  • Lillian Chong, University of Pittsburgh: Protein binding simulations with pathways and kinetics

 

04:00 – 04:30 pm

Break

04:30 – 05:30 pm

Working group formation 

05:30 – 05:45 pm

Closing presentation 

  • Yuanning Feng, Foresight Institute: The Molecular Machines Tech Tree

05:45 – 07:00 pm

Dinner

Tuesday, September  11

09:00 – 09:30 am

Arrival & Networking

09:30 – 12:30 pm

Working groups on molecular machine architectures

12:30 – 01:30 pm

Lunch (mentorship pairings)

01:30 – 03:30 pm

Group presentations

03:30 – 04:30 pm

Meta challenge session & next steps

04:30 – 06:00 pm

Aftershow drinks & exploratory breakouts

LOCATION

The Institute
San Francisco

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