Presentation: Design and Applications of Self Powered Nanobots

  • Ayusman is attempting to design synthetic active matter that exhibits emergent properties based on interactions, driven far from equilibrium
  • It must be able to code and decode information
  • Self generated energy fields are of interest here – catalysis and asymmetry
  • The structure and function of systems materials must be investigated to produce nanomachines that can perform completely unique feats
  • Applications include motion-based targeting, nanomotor information processing, tandem catalysis, analyte-triggered pumping, highly sensitive microsensors, and tuning rheology of fluids
  • Enzyme motors can accelerate diffusion or perform chemotaxis, letting them move against equilibrium
  • Nanomachine metabolons could create efficient metabolic systems
  • The most accessible fuel in the body is glucose, but having motors that use multiple sources of fuel would be ideal
  • Enzyme pumps could be used for drug delivery or drug concentration against equilibrium in the presence of substrate
  • Ayusman has a vision for a multi-investigator center for autonomous fluidic devices which is multilayered, translating theory into a technology platform
  • There was speculation on how to build in memory to the nanomachine systems, but it is currently a big challenge for the field