Current nanotechnology research spans the range from steps toward molecular machine systems and nanorobots to simple nanoscale materials modifications that can have immediate and substantial practical value, such as this example that changes the electrical charge and surface energy of a metal surface. A hat to Phy.org for reprinting this Cornell University news release written by Krishna Ramanujan “New tech application keeps bacteria from sticking to surfaces“:
Just as the invention of nonstick pans was a boon for chefs, a new type of nanoscale surface that bacteria can’t stick to holds promise for applications in the food processing, medical and even shipping industries.
The technology, developed collaboratively by researchers from Cornell University and Rensselaer Polytechnic Institute, uses an electrochemical process called anodization to create nanoscale pores that change the electrical charge and surface energy of a metal surface, which in turn exerts a repulsive force on bacterial cells and prevents attachment and biofilm formation. These pores can be as small as 15 nanometers; a sheet of paper is about 100,000 nanometers thick.
When the anodization process was applied to aluminum, it created a nanoporous surface called alumina, which proved effective in preventing surrogates of two well-known pathogens, Escherichia coli O157:H7 and Listeria monocytogenes, from attaching, according to a study recently published in the journal Biofouling. The study also investigates how the size of the nanopores changes the repulsive forces on bacteria.
“It’s probably one of the lowest-cost possibilities to manufacture a nanostructure on a metallic surface,” said Carmen Moraru, associate professor of food science and the paper’s senior author. Guoping Feng, a research associate in Moraru’s lab, is the paper’s first author.
Finding low-cost solutions to limiting bacterial attachments is key, especially in biomedical and food processing applications. “The food industry makes products with low profit margins,” said Moraru. “Unless a technology is affordable it doesn’t stand the chance of being practically applied.”
Anodized metals could be used to prevent buildups of biofilms – slick communities of bacteria that adhere to surfaces and are tricky to remove – in biomedical clean rooms and in equipment parts that are hard to reach or clean, Moraru said.
There are other strategies for limiting bacterial attachment to surfaces, including chemicals and bactericides, but these have limited applications, especially when it comes to food processing, Moraru said. With food processing, surfaces must meet food safety guidelines and be inert to food that they may contact.
Anodized metal could also have marine applications, such as keeping ship hulls free of algae.
Future work will investigate the repulsive effect of these surfaces on other bacteria, and the use of other anodized materials for this purpose.
The collaborating group from Rensselaer Polytechnic Institute is led by Diana Borca-Tasciuc, associate professor of mechanical, aerospace and nuclear engineering.
According to the research paper “Alumina surfaces with nanoscale topography reduce attachment and biofilm formation by Escherichia coli and Listeria spp.“, this treatment works on both Gram-positive and Gram-negative bacterial strains. The authors note that technology transfer for using anodic surfaces can be very rapid, so perhaps the benefits of this strain of nanotechnology, in contrast to most of the advances we comment on here, will become apparent soon.
—James Lewis, PhD
