AI for Whole Brain Circuit Mapping

Using artificial intelligence to analyze 3D electron microscopy images, the rate of recovering synpatic-level neural circuits is quickly speeding up. This technology has delivered petascale cortical circuits, and over the next few months, it will deliver the field’s next whole brain connectome, the fruit fly. This talk describes the artificial intelligence used to generate these circuits, and discusses how we can advance this technology to recover the exascale whole brain connectome of the mouse. Recovering the connectome of a whole mouse brain (exascale) will require substantial improvements in accuracy and cost to handle this 1000x scale-up from the current state-of-the-art.Recovering the connectome of a whole human brain (zettascale) will require even more dramatic improvements to handle an additional 1000x scale-up.