Presenters Sergey Young, Longevity Vision Fund – Longevity investor and visionary with a mission to extend the healthy lifespans of 1 billion people – Founder of the $100M Longevity Vision Fund—one of the few funds specializing exclusively in longevity and helping to accelerate longevity breakthroughs – Development Sponsor of Age Reversal XPRIZE, a global initiative… Continue reading Sergey Young, Longevity Vision Fund | Neil Littman, Bioverge | Longevity Investing
Summary Kristen Fortney discusses the Bioage platform and one of their most promising drugs. Bioage focuses on translating and analyzing human-derived molecular data to discover drug candidates that have already have clinical data and partial approval. Doing so allows them to rapidly bring drugs to market and focus on drugs which have the highest chance… Continue reading Kristen Fortney, Bioage | Building a pipeline of clinical-stage therapies to target aging
Summary David Furman describes the effect inflammation has on the aging process. Inflammaging – chronic inflammation which occurs as we age – takes center stage at the nexus of age related pathologies. A collaborative effort between the Buck Institute and Stanford reveals how inflammation can be measured and correlated with things like multimorbidity, aging, frailty,… Continue reading David Furman, Buck Inst. | Systems Immunology of Aging to Enable Precision Preventative Medicine
Summary In this session, Reason, co-founder and CEO of Repair Biotechnologies, offered a sneak peek into their product and technology – a Cholesterol Degrading Platform – enabled by genetically modified macrophages able to consume and degrade cholesterol plaques in arteries. Apart from showing promising results in mice, he also explained the mechanism of action based… Continue reading Atherosclerosis: The As Yet Undefeated Monster
Summary Dr. Emil Kendziorra and Aschwin De Wolf talk about the process in cryonics and cryopreservation of organs, especially brains. They also address doubts related to the damage that can be caused in the tissues of cryopreserved people, and overall dive into the state-of-the-art solutions and research in cryonics, foreshadowing what is going to be… Continue reading Emil Kendziorra & Aschwin De Wolf | Biostasis & Cryonics Q&A
Summary In this session, Alexander Fedintsev, co-founder of the Radical Life Extension biohacking group, came to discuss why biohacking is a necessary component for radical life extension, how they do biohacking in the RLE group (with a few tips for better and more scientific self-experimentation), what they already achieved (like their well-known plasmapheresis trial), and… Continue reading Alexander Fedintsev | Biohacking – A Necessary Component of a Strategy for Radical Life Extension
Summary In this session, Terrie Moffitt, professor at Duke University, and Daniel Belsky, assistant professor at Columbia University, dove into the details of a new approach to measuring aging using DNA methylation. Their Pace of Aging approach, based on which a second generation DunedinPACE algorithm was developed, looks at multiple timepoints and assesses how fast… Continue reading Daniel Belsky, Terrie Moffitt | The DunedinPoAm DNA Methylation Algorithm
Summary In this session, Michael Snyder, Professor in Genetics at Stanford University, reported the latest findings from their longitudinal trials of healthy people being profiled using various omics and wearables. The first part was focused on the necessity of collecting a healthy personal baseline, because the differences between people are much larger than significant variations… Continue reading Michael Snyder, Stanford University | Monitoring Personal Health and Ageotypes Using Big Data
Summary In this session, Michael Levin, director of the Tufts Center for Regenerative and Developmental Biology, introduced the field of bioelectricity, and the impressive regenerative potential it harbors. Michael showcased techniques that enable regrowth of limbs and formation of different organs using bioelectricity and cocktails of repurposed ion channel drugs. And he also gave an… Continue reading Bioelectric Networks: Taming the Collective Intelligence of Cells for Regenerative Medicine
Summary In this session, Daniel Ives, founder of Shift Bioscience, introduced their transcriptomic driver clock which enabled them to identify putative drug targets for safer cellular rejuvenation, which might avoid the challenges coupled to therapeutic use of Yamanaka factors. Daniel goes into detail on what the clock enables, how they are planning to validate these… Continue reading Drug Target Discovery for Cellular Rejuvenation by ‘Driver’ Clocks | Daniel Ives, Shift Bioscience
