AAAS examines impacts of nanotechnology

from the it's-about-time dept.
Although the editors of Science have generally taken a dim view of the prospects for advanced nanotechnology, somebody at American Association for the Advancement of Science (AAAS) is taking the potential ethical and socioeconomic impacts seriously. The debate over genetics, nanotech and robotics (GNR) technologies sparked by Bill Joy's notorious article in Wired last year formed a major section in the AAAS Science and Technology Policy Yearbook 2001, which is a retrospective look back at 2000.

In addition to the full text of Joyís article from Wired ("Why the Future Doesnít Need Us," April 2000), a special section of the Yearbook on "Technologyís Impact on Society" includes responses by John Seely Brown and Paul Duguid from The Industry Standard ("A Response to Bill Joy and the Doom-and-Gloom Technofuturists," 13 April 2000); a piece by Michael Dertouzos of MIT that appeared in Technology Review magazine ("Not by Reason Alone," September/October 2000); and an paper by Michael M. Crow and Daniel Sarewitz of Columbia University on "Nanotechnology and Societal Transformation" that was presented at the National Science and Technology Council Workshop on Societal Implications of Nanoscience and Nanotechnology held in September 2000.

The full AAAS Yearbook, as well as these individual items, are available online as Adobe Acrobat PDF files. There are also some interesting sections on the genetic modification of foods, and the impacts of information technologies.

Making Useful Forecasts

from the wheat-from-chaff dept.
Senior Associate Richard H. Smith presents a brief overview of the potential of nanotechnology in a cover article in Modern Drug Discovery ("Nanotechnology gains momentum," April 2001), an publication of the American Chemical Society.

Smith, who is director of forecasts in science, technology, and engineering for Coates & Jarratt, Inc., in Washington, DC., writes: "Given a continuation of current trends, a truly potent nanotechnology will likely be realized within a decade or two. It could come in the form of exquisitely precise top-down procedures, such as moving molecules around with tiny robotic 'hands', or through a massively parallel bottom-up process, such as replicating cells."

After covering a variety of short- and medium-term research and development initiatives and discussing the potential long-term possibilities, Smith concludes: "That nanotechnology, even self-assembly with intentionality, is a serious field is no longer in doubt. But how to sort useful forecasts from unsupported conjecture remains a challenge. Are artificial immune systems worthy of discussion, or should we stick with whatís here and now? Should we fund only near-term deliverables and needed infrastructure, or challenge ourselves to keep investigating speculative but beneficial possibilities? The answer is easy: We should do both."

Seeking assistance in motivating students

from the help-wanted dept.
DanKindsvater writes "I really ought to jettison a few of my projects since I'm trying to finish my master's in AI this summer, but they're all too important to me. I'd appreciate help from anyone attempting something similar, especially if you have time to chat at the Gathering this month:
1. Collect job descriptions of nanotech jobs to show to smart local (mainly UNC-G and NCA&T) graduate students, to increase local interest in nano-relevant courses;
2. Raise, or identify, scholarship money for any local students who want to put some effort into qualifying for one of the spiffy new IMM prizes;
3. Provide syllabi or other course materials for local professors who are interested in offering nano-relevant courses."

Nanotechnology on "Springboard" national public TV

from the public-education dept.
The new national (U.S.) PBS-TV show Springboard is doing a show on nanotechnology including guests Ralph Merkle, Principal Fellow, Zyvex (and Foresight Advisor); Philip Clayton, Principal Investigator, Center for Theology and Natural Sciences; Phil Kuekes, Fellow, HP Labs (and Feynman Prizewinner); Joe Haldeman, Author; and myself (Christine Peterson, President, Foresight Institute). Read More for broadcast info.

Formerly-secret trade negotiations opening up

from the openness-in-government dept.
In a stunning move reported by AP wireservice, negotiators of the proposed Free Trade Area of the Americas will make the text public prior to finalization: "A draft text of the all-Americas free trade agreement would be made public, he said. In the past, negotiations went on behind closed doors." A victory for the growing openness movement, probably stimulated by the failure of a previous international treaty draft which was deliberately leaked by the opposition.

Evolutionary protein design

from the unnatural-selection dept.
vik points out an item about researchers at the Massachusetts General Hospital in Boston who have been developing proteins with specific binding affinity by pseudo-evolutionary processes, which appeared on Natureís Science Update site. Researchers Anthony Keefe and Jack Szostak have developed a method to indetify proteins to do a predetermined job from a vast number of random genes. The article makes an explicit connection to the potential of protein design as a pathway toward nanotechnology:
"It's 20 years since Eric Drexler, one of the prophets of nanotechnology, suggested that proteins could be engineered, and that molecular machines could be used in computing or medicine. But protein design has proved damnably difficult, because of our inability to predict how a linear sequence of amino acids will fold up into a three-dimensional protein. An evolutionary approach might sidestep this problem."

Drexler's 1981 paper in the Proceedings of the National Academy of Sciences USA, which first proposed the protein engineering pathway, is cited.

vik writes: "An evolutionary approach to protein design may be more fruitful than protein-folding predictions in producing either protein-based machinery or using custom proteins as templates for the catalysis of nanoscale components."

UN University updates futures scenarios

from the imagineering dept.
Craig Hubley writes "The American Committee for the United Nations University, which I worked with for some years, recently updated its Global Scenarios which have been compiled since 1997 and include both "normative" and "exploratory" styles, in time ranges to 2025, 2500, and 3000. Of most interest are issues with respect to temporal mechanics and quantum entanglement, inter-species ethics, and the fact that almost all scenarios assume that nanotech will be used by military and "terrorist" organizations at some point. Despite that, a positivist pro-technology tone prevails throughout."

Read more for Craigís take on some of the scenarios.

Alternate pathways to assemblers?

from the Many-roads dept.
SteveLenhert at About.com writes of an item posted there that looks at an alternate approach to developing an assembler:"This essay ("Are you a Self-Assembler?") discusses an approach towards molecular nanotechnology that does not require self-replicating assemblers and can be realized using available biotechnology."

There is a related item on the site that addresses some of the same issues.

Detailed Structure Of The Ribosome Described

from the natural-molecular-manufacturing dept.
William Morgan writes "Just a reminder that there is more than one path…
A press release on EurekAlert describes an article in
Science about researchers at UC Santa Cruz who used x-ray crystallography to detail the structure of ribosomes."

In a paper published in the 30 March 2001 issue of Science, the researchers describe the structure of a bacterial ribosome in sufficient detail to begin to understand how it works. "This allows us to see what all the key parts are and how they interact," said Harry Noller, head of the group that obtained the new images. "The ribosome is a molecular machine, and it must have moving parts to accomplish its function. We are now in a position to understand the structural rearrangements of the ribosome during protein synthesis," Noller said. The abstract of the paper is freely available online.

Previous research into the fine structure of ribosomes was covered here in July and August of 2000.

Quantum-Dot Nano-Lasers

from the can-they-use-that-name? dept.
TanMauWu writes "An article in the April 2001 issue of Technology Review reports the creation of "Nanodot Lasers". These lasers can potentially output coherent light in a very wide range of frequencies, as opposed to the limited frequencies modern lasers can provide."

The lasers are semiconductor particle quantum dots — just a few nanometers across — and quantum effects tune the color of the glow to the size of the particle. The work was conducted by MIT chemist Moungi Bawendi and Victor Klimov, a laser expert at Los Alamos National Lab in New Mexico.

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