Tutorial review of the promise of artificial molecular machines

A tutorial review addresses the distinction between the many simple artificial molecular devices that are currently available and truly effective artificial molecular machines that would mimic the ubiquitous molecular machines present in living systems.

Lecture by Eric Drexler at Oxford on physical law and the future of nanotechnology (video)

In a lecture at Oxford Eric Drexler argued that atomically precise manufacturing will be the next great revolution in the material basis of civilization, and discussed how we can establish reliable knowledge about key aspects of such technologies.

Geometry of DNA nanostructures used to program molecular recognition

Adding a new molecular recognition code to structural DNA nanotechnology—a pattern of projecting and recessed blunt-end DNA helices can be used to code the assembly of DNA origami tiles into larger DNA nanostructures.

DNA nanosensors profile gene activity to reveal state of cells

Small DNA molecules fluoresce in the presence of specific transcription factors, sensing which genes are being expressed in that cell, potentially allowing cancer treatments to be personalized, and the quality of stem cells to be monitored.

Single molecule nanocar with functional wheels driven by electron tunneling

Electron tunneling drives a conformational change in each wheel of a four-wheel drive, single molecule nanocar, driving it across a copper surface.

An artificial molecular clock to control artificial molecular machines

The oscillating synthesis and degradation of regulatory RNA molecules was used to produce a molecular clock to control the opening and closing of a DNA tweezers, and also to control the production of another RNA molecule to alter the fluorescence of a dye molecule.

Using DNA as bonds to build new materials from nanoparticles

Varying the length of the DNA used to connect the nanoparticles provides for a wide variety of nanoparticle sizes and crystal symmetries.

Viruses guide nano-assembly of biomaterials

This contribution has been forwarded by Ivo Rivetta. Researchers at UC Berkeley have taken a bioinspired approach to control the nanostructure of deposited thin films. In living organisms, the orientation of collagen in tissue determines its properties: For instance, a number of blue-skinned animals, including the mandrill monkey, derive their coloring not from pigment, but… Continue reading Viruses guide nano-assembly of biomaterials

Self-replication achieved using structural DNA nanotechnology

Tiles made from DNA helices have been made to self-assemble into a more complex structure, which then was used to seed the formation of a complementary structure. This second structure in turn seeded the formation of multiple copies of the first structure.

Singularity University takes on advanced nanotech questions

The Singularity University Executive Program recently took on the challenges of advanced nanotech: Nanotechnology: How should we evaluate the environmental impact of human-made machines that are too small to see? What limits should be placed on self-replicating nanodevices? What defenses should we institute against malevolent uses of such technology? These questions were asked by Marc… Continue reading Singularity University takes on advanced nanotech questions

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