Tutorial review of the promise of artificial molecular machines

A tutorial review addresses the distinction between the many simple artificial molecular devices that are currently available and truly effective artificial molecular machines that would mimic the ubiquitous molecular machines present in living systems.

Lecture by Eric Drexler at Oxford on physical law and the future of nanotechnology (video)

In a lecture at Oxford Eric Drexler argued that atomically precise manufacturing will be the next great revolution in the material basis of civilization, and discussed how we can establish reliable knowledge about key aspects of such technologies.

New light-sensitive polymer to control drug release from nanoparticles

A new polymer that disintegrates in response to harmless radiation that can penetrate several inches into human tissue may lead to nanoparticles that release their drug cargo only at a desired time and place.

Darpa seeks nanotechnology defense against novel pathogens

To counter the threat of evolved or engineered resistance of pathogenic bacteria to antibiotics, Darpa proposes to use nanotechnology to develop “Rapidly Adaptable Nanotherapeutics”.

Geometry of DNA nanostructures used to program molecular recognition

Adding a new molecular recognition code to structural DNA nanotechnology—a pattern of projecting and recessed blunt-end DNA helices can be used to code the assembly of DNA origami tiles into larger DNA nanostructures.

DNA nanosensors profile gene activity to reveal state of cells

Small DNA molecules fluoresce in the presence of specific transcription factors, sensing which genes are being expressed in that cell, potentially allowing cancer treatments to be personalized, and the quality of stem cells to be monitored.

Leveraging nanoforces to increase biosensor sensitivity

This contribution has been forwarded by Ivo Rivetta. The primary forces on the nanometer scale are scaled versions of what we experience on a day to day basis. Instead of gravity, surface forces such as water tension and electric charge dominate. As an example, compare wet basketballs and wet sand. The weight of the basketballs… Continue reading Leveraging nanoforces to increase biosensor sensitivity

An artificial molecular clock to control artificial molecular machines

The oscillating synthesis and degradation of regulatory RNA molecules was used to produce a molecular clock to control the opening and closing of a DNA tweezers, and also to control the production of another RNA molecule to alter the fluorescence of a dye molecule.

Carbon nanotube muscles could propel future medical nanorobots (video)

Yarn woven from carbon nanotubes provides a thousand times more rotation than is obtained from other artificial muscles, and could be made into motors to provide propulsion for micrometer-sized medical nanorobots.

Using DNA as bonds to build new materials from nanoparticles

Varying the length of the DNA used to connect the nanoparticles provides for a wide variety of nanoparticle sizes and crystal symmetries.

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