Nanotechnology milestone: general method for designing stable proteins

Five proteins were designed from scratch and found to fold into stable proteins as designed, proving the ability to provide ideal, robust building blocks for artificial protein structures.

Measuring individual chemical bonds with noncontact-AFM

Noncontact atomic force microscopy using a tip functionalized with a single molecule provides highly precise measurement of individual chemical bond lengths and bond orders (roughly, bond strength).

Rational design of peptoids: a route to advanced nanotechnology?

A combination of theoretical and experimental work on peptoids, synthetic analogs of proteins, points to the ability to design peptoids with desired structures and functions.

Toward a method to design any needed catalyst?

Computational insights into a fundamental organic synthesis reaction may lead to the ability to design a catalyst for any desired reaction.

SAVE THE DATE: The 2013 Foresight Technical Conference

The 2013 Foresight Technical Conference: Illuminating Atomic Precision will be held January 11-13, 2013 in Palo Alto, CA USA.

Advancing nanotechnology with protein building blocks

A variety of protein cage structures have been constructed by designing specific protein domains to self-assemble as atomically precise protein building blocks in defined geometries.

Will piezoelectric graphene provide options for nanoscale manipulation?

Calculations using density functional theory have demonstrated that graphene can be made piezoelectric by adsorbing atoms or molecules on one surface, or by adsorbing different atoms or molecules on each surface.

Novel RNA structural motifs expand tool kit for RNA nanotechnology

New computational methods to explore the rapidly expanding collection of high resolution three-dimensional RNA structures reveal new RNA structural motifs, identifying additional building blocks for complex RNA nanostructures.

Machine learning may improve molecular design for nanotechnology

A set of machine learning programs can now predict properties of small organic molecules as accurately as can calculations based upon the Schrödinger equation, but in milliseconds rather than hours.

Crowd-sourced protein design a promising path to advanced nanotechnology

Foldit game players have again out-performed scientists in protein design, this time improving the design of a protein designed from scratch to catalyze Diels-Alder cycloadditions.

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