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        Writing a single-atom qubit in silicon

        A single-electron spin qubit on a phosphorous atom in a conventional silicon computer chip has been coherently manipulated, demonstrating the application of single atom nanotechnology to the development of a scalable platform for a quantum computer.

        More complex circuits for synthetic biology lead toward engineered cells

        One possible pathway from current technology to advanced nanotechnology that will comprise atomically precise manufacturing implemented by atomically precise machinery is through adaptation and extension of the complex molecular machine systems evolved by biology. Synthetic biology, which engineers new biological systems and function not evolved in nature, is an intermediate stage along this path. An… Continue reading More complex circuits for synthetic biology lead toward engineered cells

        Metal-organic frameworks provide large molecular cages for nanotechnology

        Large molecular cages constructed from metal-organic frameworks have set a record for the greatest surface area in the least mass.

        Metal-organic frameworks (MOFs) are back in the news again. A few months ago we cited the use of MOFs by Canadian chemists to self-assemble a molecular wheel on an axis in a solid material. More recently chemists at Northwestern University have used MOFs to set a world record for surface area. From “A world record for highest-surface-area materials“:

        Northwestern University researchers have broken a world record by creating two new synthetic materials with the greatest amount of surface areas reported to date.

        Named NU-109 and NU-110, the materials belong to a class of crystalline nanostructure known as metal-organic frameworks (MOFs) that are promising vessels for natural-gas and hydrogen storage for vehicles, and for catalysts, chemical sensing, light harvesting, drug delivery, and other uses requiring a large surface area per unit weight.

        The materials’ promise lies in their vast internal surface area. If the internal surface area of one NU-110 crystal the size of a grain of salt could be unfolded, the surface area would cover a desktop. …

        MOFs are composed of organic linkers held together by metal atoms, resulting in a molecular cage-like structure. The researchers believe they may be able to more than double the surface area of the materials by using less bulky linker units in the materials’ design. …

        Beyond their near-term practical applications, Eric Drexler has cited MOFs as potentially useful building blocks in the molecular machine path to molecular manufacturing. Near-term applications may drive the technology development to produce more choices for molecular machine system components.
        —James Lewis, PhD

        Measuring individual chemical bonds with noncontact-AFM

        Noncontact atomic force microscopy using a tip functionalized with a single molecule provides highly precise measurement of individual chemical bond lengths and bond orders (roughly, bond strength).

        AI for synthetic chemistry may provide more building blocks for nanotechnology

        Millions of organic chemicals and reactions have been incoporated into a huge computer network along with search algorithms to find new synthetic pathways. A way to find new building blocks for molecular nanotechnology?

        Toward a method to design any needed catalyst?

        Computational insights into a fundamental organic synthesis reaction may lead to the ability to design a catalyst for any desired reaction.

        3D printers as universal chemistry sets for nanotechnology

        Researchers have configured a 3D printer as an inexpensive, automated discovery platform for synthetic chemistry. A road to more complex molecular building blocks for nanotechnology?

        New online game to design RNA molecules: advancing nanotechnology?

        A new online game allows players to design RNA molecules. The most promising designs are synthesized, and the players given real-world feedback on how well their designs worked.

        Solid state synthetic molecular machine points to advanced nanotechnology

        Interlocking organic molecules held between copper atoms have been assembled in a void inside a solid state material to create a very simple molecular machine, a wheel that spins around an axle.

        An expanded genetic alphabet could lead to more easily designed proteins

        The demonstration that the process of DNA replication is more flexible than thought should make it easier to incorporate unusual amino acids into designed proteins, which might make it easier to design novel protein machines.

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