Nanomedicine

Ultrafast DNA robotic arm: A step toward a nanofactory?

By | 2018-01-25T12:37:45+00:00 January 25th, 2018|Artificial Molecular Machines, Atomically Precise Manufacturing (APM), Bionanotechnology, Energy, Future Medicine, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Research, World-Shaping Technologies|

Electric fields drive the rotating nano-crane – 100,000 times faster than previous methods. (Image: Enzo Kopperger / TUM) Rotation of the arm between two docking points (red [...]

Design of hyperstable constrained peptides

By | 2018-01-17T12:23:26+00:00 January 17th, 2018|Atomically Precise Manufacturing (APM), Bionanotechnology, Computational nanotechnology, Foresight Kudos, Future Medicine, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Productive Nanosystems, Research, World-Shaping Technologies|

Sixteen topologies of de novo designed hyperstable constrained peptides. Credit: Baker lab, University of Washington Protein design has been one of the major paths from current fabrication technology toward [...]

Two-component, 120-subunit icosahedral cage extends protein nanotechnology

By | 2017-09-26T16:37:11+00:00 January 28th, 2017|Atomically Precise Manufacturing (APM), Bionanotechnology, Computational nanotechnology, Energy, Foresight Kudos, Future Medicine, Molecular manufacturing, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Productive Nanosystems, Research|

Ten designs spanning three types of icosahedral architectures produce atomically precise multi-megadalton protein cages to deliver biological cargo or serve as scaffolds for organizing various molecular functions.

DNA nanotechnology defeats drug resistance in cancer cells

By | 2017-06-01T14:01:38+00:00 April 2nd, 2016|Bionanotechnology, Future Medicine, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Research|

Small, stiff, rectangular rods made using scaffolded DNA origami bypass drug resistance mechanisms in the membranes of a cultured leukemia cell line and release enough therapeutic drug to kill the cancer cell.

DNA nanotechnology cages localize and optimize enzymatic reactions

By | 2017-06-01T14:01:39+00:00 February 16th, 2016|Bionanotechnology, Future Medicine, Molecular Nanotechnology, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Research|

Encapsulating enzymes in nanocages engineered using structural DNA nanotechnology increases enzymatic digestion and protects enzymes from degradation.

DNA nanotechnology controls which molecules enter cells

By | 2017-06-01T14:01:40+00:00 January 13th, 2016|Atomically Precise Manufacturing (APM), Bionanotechnology, Future Medicine, Molecular manufacturing, Molecular Nanotechnology, Nanobiotechnology, Nanodot, Nanomedicine, Nanotech, Nanotechnology, Research|

DNA building blocks mimic biological ion channels to more precisely control which molecules can cross a biological membrane.

Nanoparticles ameliorate MS in mice by inducing immune tolerance of myelin

By | 2017-06-01T14:22:08+00:00 January 7th, 2016|Bionanotechnology, Future Medicine, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanoscale Bulk Technologies, Nanotech, Nanotechnology, Research|

In the first mouse model of the progressive form of multiple sclerosis, nanoparticles that created immune tolerance to myelin prevented the development of progressive MS.

Rolling DNA-based motors increase nano-walker speeds 1000-fold

By | 2017-06-01T14:01:41+00:00 December 12th, 2015|Bionanotechnology, Future Medicine, Healing/preserving environment, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanoscale Bulk Technologies, Nanotech, Nanotechnology, Research|

Coating micrometer-sized glass spheres with hundreds of DNA strands complementary to an RNA covering a glass slide enables the sphere to move, with the help of an enzyme that digests RNA bound to complementary DNA, a thousand times faster than conventional DNA-walkers.

Novel nanoconjugate delivers synergistic combination of microRNAs to treat cancer

By | 2017-06-01T14:01:41+00:00 December 11th, 2015|Bionanotechnology, Future Medicine, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanoscale Bulk Technologies, Nanotech, Nanotechnology, Research|

Two microRNAs with synergistic effects, one that suppresses tumor growth and another than inhibits tumor promotion, are combined in an RNA triple helix, complexed with a dendrimer to form nanoparticles, which are incorporated with a polymer to form a hydrogel that inhibits tumor growth when applied to the tumor.

Ultrasensitive microRNA assay with nanosensor to detect cancer

By | 2017-06-01T14:01:41+00:00 December 10th, 2015|Bionanotechnology, Future Medicine, Nano, Nanobiotechnology, Nanodot, Nanomedicine, Nanoscale Bulk Technologies, Nanotech, Nanotechnology, Research|

A nanotechnology-based sensor provides fast, inexpensive, ultrasensitive assay of microRNA pattern to detect cancer using DNA immobilized on a synthetic gold nanoprism.