SAVE THE DATE: The 2013 Foresight Technical Conference

The 2013 Foresight Technical Conference: Illuminating Atomic Precision will be held January 11-13, 2013 in Palo Alto, CA USA.

Atomically precise nanoparticle provides better drug delivery

Nanoparticles made from specific DNA and RNA strands, homogeneous in size, composition, and surface chemistry, proved superior to other nanoparticles in silencing gene expression in tumors in mouse experiments.

Nanomachines and molecular motors can make use of thermal noise

A theoretical study shows that although thermal noise cannot be used to produce useful motion by mesoscale or macroscale machines, it can be used by nanoscale machines without violating the second law of thermodynamics.

An expanded genetic alphabet could lead to more easily designed proteins

The demonstration that the process of DNA replication is more flexible than thought should make it easier to incorporate unusual amino acids into designed proteins, which might make it easier to design novel protein machines.

New method to identify intermediates in protein folding

Tryptophan residues introduced at various positions in a protein chain identify folding intermediates that are too short-lived to be structurally characterized otherwise.

Advancing nanotechnology with protein building blocks

A variety of protein cage structures have been constructed by designing specific protein domains to self-assemble as atomically precise protein building blocks in defined geometries.

DNA tiles provide faster, less expensive way to fabricate complex DNA objects

A set of 310 short single-stranded DNA tiles, plus a few additional short sequences for the edges, has been used to form more than a hundred large, complex DNA objects.

New Darpa program may accelerate synthetic biology path to advanced nanotechnology

Darpa has launched a “Living Foundries” program to bring an engineering perspective to synthetic biology to greatly accelerate progress through standardization and modularization.

Foresight Institute on Singularity Hub (video)

Recent interview touches on new Foresight programs and issues in nanotechnology development

Will piezoelectric graphene provide options for nanoscale manipulation?

Calculations using density functional theory have demonstrated that graphene can be made piezoelectric by adsorbing atoms or molecules on one surface, or by adsorbing different atoms or molecules on each surface.

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