Tailoring the shapes of organic molecules by assembly-line synthesis

To emulate the process by which nature assembles complex organic molecules by passing subunits through a series of enzyme domains, UK chemists developed a procedure to elongate a boronic ester by using a reagent that inserts into carbon-boron bonds with precise control of molecular configuration.

Nanomanufacturing grants available from US National Science Foundation

The US NSF has announced a program to support fundamental research leading to complex nanosystems.

Scaffolded DNA origami improvements advance DNA nanotechnology

A 10-fold larger breadboard and 350-fold lower DNA synthesis costs make DNA origami a more useful stepping-stone toward atomically precise manufacturing.

What kind of nanomachines will advanced nanotechnology use?

An interview with UK nanotechnologist Richard Jones argues that the surest and most efficient path to advanced nanomachine function will incorporate or mimic biomolecular nanomachinery rather than scaled down rigid conventional machinery.

Emergence of nanobiotechnology points to importance of deep collaboration

Study shows more than 500 firms involved in nanobiotechnology, which is expected to soon triple in size. Research points to the importance of broad networks and deep collaborations.

Biotech lab in the cloud lowers entry barrier to nanotech research

With biotech fundamental to several paths to advanced nanotechnology, a way to do biotech experiments in the cloud offers small groups the chance to quickly test their ideas.

Building biological molecular machines as an open source path to advanced nanotechnology

B.R.AI.N.S., Berkeley BioLabs, and Foresight Institute to build an open source biological parts repository and design and distribute a line of “How-to Build Biological Machines” educational kits.

Lipid coat protects DNA nanorobot from immune attack

Enveloped DNA nanostructures were developed to escape attacks from nucleases and the immune system, opening a path to ever more sophisticated DNA nanomedical devices.

Robust triangular RNA brick adds to RNA nanotechnology toolkit

The complex molecular recognition code of RNA offers RNA nanotechnology a greater variety of 3D structures and functions than are present in DNA nanotechnology, but the RNA structures can be fragile. New RNA triangles that resist boiling solve this problem.

DNA nanotechnology replicates enzyme cascade

A swinging DNA arm added to a DNA scaffold makes it possible for two enzymes attached to the scaffold to complete a coupled chemical reaction.

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