Physicists suppress ‘stiction’ force that bedevils microscale machinery

A possible top-down path to atomically precise manufacturing that passes through microscale machinery might be rendered easier because of recent progress in suppressing the Casimir force, which contributes to the ‘stiction’ problem often encountered with microelectromechanical systems.

Programmable nanoprocessors integrated into a nanowire nanocomputer

Pioneering a design and fabrication strategy to address individual nanoscale electronic devices to enable large-scale assembly into integrated computer circuits, a MITRE-Harvard team has assembled a functional nanoelectronic control computer.

Bigger, stiffer, roomier molecular cages from structural DNA nanotechnology

Using struts made of DNA to stiffen polyhedral corners, scientists have build rigid DNA cages an order of magnitude larger than previous DNA nanostructures, and only one order of magnitude smaller than bacterial cells.

Chemists provide new tool for nanotechnology-modifying the right carbon atom

A new tool to chemically modify one specific carbon atom among several chemically very similar ones will facilitate building larger, more complex molecules for drug discovery and for nanotechnology.

Will crowdsourced RNA designs advance nanotechnology?

A very large community of online gamers has consistently produced RNA designs that outperform the best design algorithms by a large margin. Can online gamers designing RNA, protein, and other molecules contribute to the development of atomically precise manufacturing?

In mice, nanoparticle reduces inflammation in atherosclerotic plaques

A reconstituted high-density lipoprotein nanoparticle reduces inflammation in advanced atherosclerotic plaques in mice. Will it work in humans to prevent repeat heart attacks and stroke?

Better nanoswitches by integrating double and triple strand DNA

A DNA clamp engineered for higher specificity and higher affinity may improve cancer diagnosis and treatment and may also mean better control over building nanomachines.

Integrating DNA nanotechnology and RNA to transport nanoparticles along nanotubes

A possible forerunner to a future molecular assembly line uses an artificial DNA motor to transport an artificial nanoparticle along a carbon nanotube track.

RNA nanotechnology – fewer structures in living cells than in test tubes

A study of RNA structures actually present in cells reveals that cells spend energy restricting thermodynamically driven RNA folding so that fewer RNA structures are found in cells than in test tubes.

Advanced technologies by design

Design and prediction are integral to Atomically Precise Manufacturing and its development. This is in part because fully functional APM can be readily explored computationally today, to levels of precision that cannot be experimentally developed today. In such a context, design is not just a resource but an approach. With rapidly expanding computational power, examples… Continue reading Advanced technologies by design

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