Tailoring the shapes of organic molecules by assembly-line synthesis

To emulate the process by which nature assembles complex organic molecules by passing subunits through a series of enzyme domains, UK chemists developed a procedure to elongate a boronic ester by using a reagent that inserts into carbon-boron bonds with precise control of molecular configuration.

Nanomanufacturing grants available from US National Science Foundation

The US NSF has announced a program to support fundamental research leading to complex nanosystems.

DNA nanotechnology and the atoms to micrometer nanofabrication gap

A new DARPA program seeks to bridge the gap from atoms to macroscale product manufacture in two steps, the first of which is from atoms to micrometer-scale feedstocks. DNA origami may be part of the solution.

Scaffolded DNA origami improvements advance DNA nanotechnology

A 10-fold larger breadboard and 350-fold lower DNA synthesis costs make DNA origami a more useful stepping-stone toward atomically precise manufacturing.

Novel multifunctional nanoparticle for diagnosis and therapy

A nanoparticle that self-assembles from porphyrin, cholic acid, amino acids, and polyethylene glycol is a promising vehicle for delivering both imaging agents and cancer drugs to tumors.

Proof of principle for nanoscale assembly line

Swiss researchers have used biomolecular shuttles to capture molecular building blocks from solution and transport them across fluid flow boundaries to be further manipulated in a subsequent chamber.

DARPA announces new program on nanoscale assembly and integration

Register by Sept. 5 to attend a Proposers Day webinar on either Sept. 9 or 11 to learn the technical objectives of DARPA’s new “Atoms to product: Aiming to make nanoscale benefits life-sized” program.

What kind of nanomachines will advanced nanotechnology use?

An interview with UK nanotechnologist Richard Jones argues that the surest and most efficient path to advanced nanomachine function will incorporate or mimic biomolecular nanomachinery rather than scaled down rigid conventional machinery.

Seeing and touching a single synthetic molecular machine

Attaching a 200-nm-diameter magnetic bead to a 1-nm diameter synthetic molecular machine allowed optical visualization of the motion of the machine and manipulation with a magnetic tweezers.

Recent cases of &#39accessible&#39 high-tech: Open source chips & Origami robots

Nanotech promises more commonplace access to advanced technology as material and fabrication costs fall and traditional barriers to innovation are removed. Examples are already being seen globally: more access to laptops and cell phones in developing countries, desktop 3D printers, a surge in establishment of shared-use research facilities, etc. A couple recent cases getting attention… Continue reading Recent cases of &#39accessible&#39 high-tech: Open source chips & Origami robots

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