Swarms of DNA nanorobots execute complex tasks in living animal

Combinations of different types of DNA nanorobots, implementing different logic gates, work together to tag a specific type of cell in a living cockroach depending on the presence or absence of two protein signals.

Small molecule nanorobot walks through a protein nanopore

Among the smallest molecular robots reported so far, a walker based on phenylarsonous acid with two organic thiol ligands as feet walks through a one-nanometer-diameter protein nanopore channel by taking 0.6 nanometer steps, by thiol exchange, from one cysteine residue to the next.

Computational framework for structural DNA nanotechnology

A more general computational framework predicts the structures of 2D and 3D-curved DNA nanostructures impossible to predict using previously available computational methods. May lead to 3D-printing DNA nanostructures?

New way to couple carbon atoms yields novel molecular architectures

A new strategy to form bonds between carbon atoms opens the way to a wide variety of molecular architectures that had been difficult or impossible to access using previous methods.

Artificial enzymes created from building blocks not found in nature

Artificial enzymes have been created from nucleic acids that use synthetic molecules instead of ribose or deoxyribose sugars.

Large, open protein cages designed and built

Design principles have been developed and tested to construct novel synthetic protein monomers that can self-assemble into large, open protein cages for potential use in vaccines and drug delivery.

Broadening the synthetic biology path to molecular nanotechnology

Advances in the de novo design of coiled-coil proteins made by two different research groups proceeding by two different routes demonstrate that the range of protein nanostructures potentially available for various molecular machine systems is significantly larger than the range of such structures already exploited by natural selection.

Micrometer-scale structures built from DNA bricks

A general framework is presented for using 32-nucleotide DNA bricks to build large two-dimensional crystals up to 80 nm thick and incorporating sophisticated three-dimensional features.

Using DNA nanotechnology to cast arbitrarily shaped nanoparticles

Metal or other inorganic nanoparticles of 20 to 30-nm scale can be cast in arbitrary 3D shapes and configurations dictated by stiff, atomically precise molds constructed using scaffold DNA origami.

Grant program to support nanotechnology and other infrastructure

The US National Science Foundation announced a new grant program to develop and apply next-generation networking to advance nanotechnology and other emerging technologies to meet important national needs.

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