New advancement in 3D imaging of nanoparticles at atomic resolution

Researchers from UCLA’s California NanoSystems Institute and Northwestern University have combined multiple imaging techniques to produce high quality 3D images of platinum nanoparticles, allowing advanced visualization of atomic-scale structural defects (an important advancement over X-ray crystallography). The original 2012 work, published in Nature and posted by Jim Lewis here, used electron tomography to study 10-nm… Continue reading New advancement in 3D imaging of nanoparticles at atomic resolution

Computationally designed peptide sneaks nanoparticles past immune system

Nanoparticles decorated to avoid immune system recognition were tested in mice and shown to survive longer and deliver more imaging dye and drug to tumor cells.

Studying environmental impacts of nanoparticles using mesocosms

The advent of new technologies is typically followed by new government regulation, and in the absence of data, fear-based reactionism can have far too much influence on policy. Quality research studies on real risks and impacts of nanoscale technologies can help lead to legitimate scientific consensus and appropriate regulation. Engineered nanoparticles draw particular attention, because… Continue reading Studying environmental impacts of nanoparticles using mesocosms

Nanotechnology delivers potent anti-cancer agent where it needs to go

Core-shell nanocapsules deliver a potent protein complex to the nucleus of cancer cells where it induces them to commit suicide, while the complex degrades harmlessly in the cytoplasm of normal cells.

Toward molecular fabrication: formation of distinct bond types by STM

Scanning probe manipulation of individual atoms and small molecules were amongst the early laboratory successes that helped bring broad scale attention to the feasibility and potential of nanoscale technologies, especially molecular fabrication. Basic manipulations of atoms and bonds by scanning probe have become familiar capabilities that follow similar protocols: the STM tip is precisely positioned… Continue reading Toward molecular fabrication: formation of distinct bond types by STM

Synthetic biology industrial revolution inspires hope for molecular manufacturing

A demonstration that most fundamental biological processes can be implemented in a test tube as efficiently as in live bacteria provides synthetic biology the tools to create a ‘new industrial revolution’, which may or may not lead to more general molecular manufacturing.

Artificial molecular machine synthesizes a small peptide

A small molecular machine based on a rotaxane molecule autonomously added three amino acids in a programmed order to a seed tripeptide to form a hexapeptide

Controlled stepwise rotation on a single atom bearing

Electrons from a scanning tunneling microscope tip turn a five-arm rotor connected via a single ruthenium atom bearing to a tripod anchoring the molecular motor to a gold surface.

Nanometer-scale optical positioning and focusing

A theoretical proposal for optical tweezers and an experimental optical focusing device both depend upon electromagnetic waves trapped and guided along metal-insulator interfaces. Will these advances provide tools for manipulating molecular building blocks?

Testing and improving scaffolded DNA origami for molecular nanotechnology

In two different sets of experiments a German research group has shown that scaffolded DNA origami can be used to assemble complex structures with precise sub-nanometer positional control, and that constant temperature reaction can greatly increase yields and decrease production times.

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