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Gaming the Future: The Book!

Category: Roadmaps

Unrelated de novo enzyme replaces essential enzyme in cell

The first proposal of a path from then current technology to the ability to fabricate complex materials and devices by placing the atoms where you want them was made by Richard Feynman in 1959: “There’s Plenty of Room at the Bottom“, but see also this series “Feynman Path to Nanotechnology“. The second proposal to achieve… Continue reading Unrelated de novo enzyme replaces essential enzyme in cell

Changing the world with a nanofabricator that could make anything

The Foresight Institute was founded in 1986 on a vision presented by Eric Drexler in which the ultimate manufacturing technology uses a machine termed a nanofactory or nanofabricator to provide atom-by-atom control of the manufacturing process for complex objects, both large and small. Although initially controversial, this vision has been increasingly accepted over the past… Continue reading Changing the world with a nanofabricator that could make anything

Building atom-by-atom on insulator at room temperature

If the above picture reminds you of something like it some 27 years ago when physicists announced a nanostructure built atom-by-atom, then it is important to recognize there are multiple crucial differences between the above 2014 image of a Swiss cross formed from 20 precisely placed bromine atoms and the 1990 image of the IBM… Continue reading Building atom-by-atom on insulator at room temperature

Molecular robot builds four types of molecules

Since winning the 2007 Foresight Institute Feynman Prize in Nanotechnology, Theory category, Professor David Leigh FRS FRSE FRSC MAE, and since 2012 at the University of Manchester, has continued to achieve major milestones on the road to complex systems of molecular machinery. Contributions we have recently cited here: First direct measurement of force generated by… Continue reading Molecular robot builds four types of molecules

From de novo protein design to molecular machine systems

A review from the group leading recent rapid progress in de novo protein design describes the successes, identifies the remaining challenges, and heralds the advance “from the Stone Age to the Iron Age” in protein design.

New Funding Opportunity from U.S. DOE

A new funding opportunity from the Advanced Manufacturing Office, U.S. Department of Energy, incudes a subtopic on Atomically Precise Manufacturing

DOE office focusing on atomically precise manufacturing

Longtime Foresight member Dave Forrest is leading DOE’s Advanced Manufacturing Office in advocating atomically precise manufacturing to transform the U.S. manufacturing base.

Automated design of polyhedral meshes for DNA origami

An automated design process folds arbitrary meshes to produce DNA origami structures difficult to design by previous methods, including more open structures that are stable in ionic conditions used in biological assays.

Google Tech Talk video by Feynman Prize Winner

Designing and building spiroligomers, robust building blocks of various 3D shapes made from unnatural amino acids, decorated with various functional groups, and linked rigidly together by pairs of bonds, and a new approach to nanotechnology design software.

Preserving protein function in DNA-protein nanostructures

Linking proteins to DNA scaffolds to produce complex functional nanostructures can require chemistry that damages protein function. A new systematic approach avoids exposing proteins to damaging conditions.

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