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Gaming the Future: The Book!

Category: Molecular manufacturing

Conference video: Artificial Biochemistry with DNA

Modeling DNA strand displacement cascades according to three simple rules can in principle mimic the temporal dynamics of any other chemical system, presenting a method to model regulatory networks even more complicated than those of biology.

Automated design of polyhedral meshes for DNA origami

An automated design process folds arbitrary meshes to produce DNA origami structures difficult to design by previous methods, including more open structures that are stable in ionic conditions used in biological assays.

Facilitating structural DNA nanotechnology with non-aqueous solvents

Recent research demonstrates that certain non-aqueous solvents can not only be used to assemble DNA nanostructures, but offer certain advantages over conventional aqueous solvents.

Conference video: Conformational and compositional dynamics of a molecular machine

At the 2013 Conference Joseph Puglisi described how single molecule fluorescence techniques were used to study changes in the conformation and composition of the ribosome, a large biomolecular nanomachine, during the process of translation of genetic information.

Wafer-scale atomically precise thin layers for nanotechnology

By precise control of several factors, uniform high-performance monolayers of the semiconductor MoS2 have been obtained and used to fabricate field-effect transistors.

Google Tech Talk video by Feynman Prize Winner

Designing and building spiroligomers, robust building blocks of various 3D shapes made from unnatural amino acids, decorated with various functional groups, and linked rigidly together by pairs of bonds, and a new approach to nanotechnology design software.

US OSTP seeking suggestions for Nanotechnology Grand Challenges

A US government Request for Information (RFI) is seeking suggestions for Nanotechnology-Inspired Grand Challenges for the Next Decade. The manufacture of atomically-precise materials is offered as #4 of 6 examples.

Conference video: Regenesis: Bionano

At the 2013 Conference George Church presented an overview of his work in developing applications of atomically precise nanotechnology intended for commercialization, from data storage to medical nanorobots to genomic sequencing to genomic engineering to mapping individual neuronal functioning in whole brains.

Computational nanotechnology to benefit from expanded first-principles molecular dynamics

A combination of techniques has made possible the expansion of problems that can be handled by first-principles molecular dynamics from a few hundred atoms to a very large system containing 32,768 atoms.

Preserving protein function in DNA-protein nanostructures

Linking proteins to DNA scaffolds to produce complex functional nanostructures can require chemistry that damages protein function. A new systematic approach avoids exposing proteins to damaging conditions.

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