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Presenters William Shih, Harvard University William is overseeing an effort to apply Synthetic Biology approaches to the development of self-assembling DNA nanostructures and devices for use in biomedical applications. To achieve structures of even greater complexity, his laboratory is pioneering methods for hierarchical assembly of these particles into three-dimensional networks with site-specific control over chemical… Continue reading Molecular Detection via DNA Nanotech & Neural Nets | William Shih, Harvard & Lulu Qian, Caltech
Summary An overview of projects spearheaded by the Advanced Manufacturing Office of the US Department of Energy. These projects, involving Atomically Precise Manufacturing, are part of a larger vision for energy efficiency. The diverse portfolio of projects includes molecular assembler tips, molecular lego, diamondoid tools, copper/carbon hybrid materials, DNA origami, and Microelectromechanical systems. Presenters Tina… Continue reading AMO’s Program in Atomically Precise Manufacturing and Nanocarbon Metals | Tina Kaarsberg, DOE
Summary James Cooper discusses The Foresight Institute, future directions and goals for the Molecular Machines group. We seek to create an inclusive community of forward thinkers and doers who are interested in nanotechnology. A fantastic array of projects and contributors is lined up and more interesting projects are always being added. Attend the online discussions… Continue reading Molecular Machines Group Launch | James Cooper, University of Reading
Summary James Cooper discusses The Foresight Institute, future directions and goals for the Molecular Machines group. We seek to create an inclusive community of forward thinkers and doers who are interested in nanotechnology. A fantastic array of projects and contributors is lined up and more interesting projects are always being added. Attend the online discussions… Continue reading What Does The Future Hold For Molecular Machines? | James Cooper, University of Reading
July 2018 Update: Future of Civilization: Extinction, Race To The Bottom or Upward Climbing? – New salon videos and more exciting news In this update, find out how we have been helping the progress of beneficial technology:1. watch our latest (and amazing) salon video2. learn about the promising advances of our fellows in nanotechnology3. take action to co-create… Continue reading The Future of Civilization: Extinction, Race To The Bottom or Upward Climbing? – Foresight’s latest salon videos and more exciting news
Ultrafast molecular machines made using DNA nanotechnology have now been demonstrated. Over the past several years molecular machines made using DNA nanotechnology, especially the scaffolded DNA origami technology, have grown more complex and more functional (see, for example, here, here, here, and here). Long-time Foresight member Dr. Robert P. Meagley writes to point out that… Continue reading Ultrafast DNA robotic arm: A step toward a nanofactory?
Mechanically interlocked molecules (MIMs), such as rotaxanes and catenanes, provide a fertile opportunity to study some of the complexities of large biological systems of molecular machines, composed of large protein molecules, with small molecular machines composed of small organic molecules containing components that can move relative to each other in response to external control. The… Continue reading Mechanical communication in a rotaxane molecular machine
In writing for this blog, I am accustomed to rapid changes from one technological area to another, such as from DNA origami to de novo protein design to scanning probe microscopy to molecular machinery based on mechanically interlocked molecular architectures. The DNA and protein work overlaps with biotechnology, and we have always seen all these… Continue reading Blockchains, Cryptoeconomics, and Emerging Technology Risks
Structural DNA nanotechnology: progress toward a precise self-assembling three dimensional scaffold by building macroscopic crystals from nanoscale structures.
Small, stiff, rectangular rods made using scaffolded DNA origami bypass drug resistance mechanisms in the membranes of a cultured leukemia cell line and release enough therapeutic drug to kill the cancer cell.
