Unrelated de novo enzyme replaces essential enzyme in cell
Iron-rich medium supports the growth of E. coli engineered to no longer have a natural Fes enzyme. They form small, unhealthy, red colonies because they accumulate iron bound to [...]
Iron-rich medium supports the growth of E. coli engineered to no longer have a natural Fes enzyme. They form small, unhealthy, red colonies because they accumulate iron bound to [...]
Electric fields drive the rotating nano-crane – 100,000 times faster than previous methods. (Image: Enzo Kopperger / TUM) Rotation of the arm between two docking points (red [...]
The structural formula of the rotaxane 1H3+. Above: The dibenzo[24]crown-8 macrocycle circles the dibenzylammonium site on the left end of the axle, which had been protonated by the addition [...]
Since winning the 2007 Foresight Institute Feynman Prize in Nanotechnology, Theory category, Professor David Leigh FRS FRSE FRSC MAE, and since 2012 at the University of Manchester, has continued to [...]
If the current is high enough, the molecule starts to move and can be steered over the racetrack (University of Basel) Our previous post announced a race around [...]
Six NanoCars, each a unique concept created from only several dozen atoms by one of six teams representing six nations, and powered by electrical pulses, will compete to complete a 100 nm course within 38 hours.
A review from the group leading recent rapid progress in de novo protein design describes the successes, identifies the remaining challenges, and heralds the advance "from the Stone Age to the Iron Age" in protein design.
Sir J. Fraser Stoddart, winner of 2007 Foresight Feynman Prize for Experiment, shares the 2016 Chemistry Nobel for the design and synthesis of molecular machines.
Removing the necessity of providing several different chemical fuels in a series of distinct steps, a novel chemically-fueled molecular motor autonomously produces movement as long as the fuel supply lasts.
Recent research documents a structure-based rational design strategy combining molecular dynamics and single molecule imaging to improve the performance of a DNA tweezers that accurately positions an enzyme and its cofactor.