Unrelated de novo enzyme replaces essential enzyme in cell
Iron-rich medium supports the growth of E. coli engineered to no longer have a natural Fes enzyme. They form small, unhealthy, red colonies because they accumulate iron bound to [...]
Iron-rich medium supports the growth of E. coli engineered to no longer have a natural Fes enzyme. They form small, unhealthy, red colonies because they accumulate iron bound to [...]
Sixteen topologies of de novo designed hyperstable constrained peptides. Credit: Baker lab, University of Washington Protein design has been one of the major paths from current fabrication technology toward [...]
Image Credit: 3DSculptor / Shutterstock.com The Foresight Institute was founded in 1986 on a vision presented by Eric Drexler in which the ultimate manufacturing technology uses a machine termed [...]
It’s not red and white, but the atoms are arranged in the shape of a Swiss cross (Credit: Physics department, University of Basel) If the above picture reminds you [...]
Since winning the 2007 Foresight Institute Feynman Prize in Nanotechnology, Theory category, Professor David Leigh FRS FRSE FRSC MAE, and since 2012 at the University of Manchester, has continued to [...]
A review from the group leading recent rapid progress in de novo protein design describes the successes, identifies the remaining challenges, and heralds the advance "from the Stone Age to the Iron Age" in protein design.
Ten designs spanning three types of icosahedral architectures produce atomically precise multi-megadalton protein cages to deliver biological cargo or serve as scaffolds for organizing various molecular functions.
A new funding opportunity from the Advanced Manufacturing Office, U.S. Department of Energy, incudes a subtopic on Atomically Precise Manufacturing
Longtime Foresight member Dave Forrest is leading DOE's Advanced Manufacturing Office in advocating atomically precise manufacturing to transform the U.S. manufacturing base.
Sir J. Fraser Stoddart, winner of 2007 Foresight Feynman Prize for Experiment, shares the 2016 Chemistry Nobel for the design and synthesis of molecular machines.