Computational nanotechnology Archives

Gaming the Future: The Book!

Rational improvement of DNA nanodevice function

Recent research documents a structure-based rational design strategy combining molecular dynamics and single molecule imaging to improve the performance of a DNA tweezers that accurately positions an enzyme and its cofactor.

Atomically precise location of dopants a step toward quantum computers

Precise matching of STM images and theoretical calculations provides exact lattice locations of dopant atoms, advancing the prospects for silicon-based quantum computers.

Watching individual chemical bonds during a reaction

Combining computational nanotechnology with a noncontact-atomic force microscope probe tipped by a single CO molecule allowed researchers to visualize the dance of individual chemical bonds during a complex organic reaction on a silver surface.

Peptoid nanosheets assemble by different design rule

Chains of monomers joined by non-biological peptoid bonds follow different rules of self-assembly and form structures not found in chains joined by the peptide bonds used to form proteins.

Engineered protein assembles molecules into atomically precise lattice

An engineered protein controls the assembly of C₆₀ fullerene molecules into an atomically precise lattice that conducts electricity while neither component alone would.

Simulation of quantum entanglement with subsurface dopant atoms

Atomic resolution measurement of quasi-particle tunneling maps of spin-resolved states reveals interference processes that allow simulation of processes important for developing quantum computers based on atomically precise doping of silicon.

Protein design provides a novel metabolic path for carbon fixation

Computational design of an enzyme that carboligates three one-carbon molecules to form one three-carbon molecule, an activity that does not exist in nature, provides proof-of-principle for a novel metabolic pathway for carbon fixation.

Crowd-sourced RNA structure design uncovers new insights

Thousands of amateurs playing the online RNA folding game Eterna, backed up by a real-world automated lab testing their predictions, have provided insights to improve the algorithms computers use to design RNA molecules.

Multiple advances in de novo protein design and prediction

New families of protein structures, barrel proteins for positioning small molecules, self-assembling protein arrays, and precision sculpting of protein architectures highlight de novo protein design advances.

Rational design of protein architectures not found in nature

Computational design of proteins satisfying predetermined geometric constraints produced stable proteins with the designed structure that are not found in nature.

Gaming the Future: The Book!

Category: Computational nanotechnology

Rational improvement of DNA nanodevice function

Atomically precise location of dopants a step toward quantum computers

Watching individual chemical bonds during a reaction

Peptoid nanosheets assemble by different design rule

Engineered protein assembles molecules into atomically precise lattice

Simulation of quantum entanglement with subsurface dopant atoms

Protein design provides a novel metabolic path for carbon fixation

Crowd-sourced RNA structure design uncovers new insights

Multiple advances in de novo protein design and prediction

Rational design of protein architectures not found in nature

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