Ultrasensitive microRNA assay with nanosensor to detect cancer

A nanotechnology-based sensor provides fast, inexpensive, ultrasensitive assay of microRNA pattern to detect cancer using DNA immobilized on a synthetic gold nanoprism.

Using DNA nanotechnology to position molecules with atomic precision

German researchers have used scaffolded DNA origami to adjust the angle of a DNA hinge joint by altering the length of special “adjuster helices”, causing molecules attached to the sides of the hinge to be displaced by as little as 0.04 nm.

DNA nanomachine lights up to diagnose diseases

DNA nanotechnology produces an artificial molecular machine that changes shape when it encounters a specific antibody or other protein molecule, and emits light to signal the target’s presence.

Surface assisted self-assembly of DNA origami nanostructures

A lipid bilayer supported by a mica surface assisted the mobile self-assembly of DNA nanostructures of various shapes into micrometer-scale 2D lattices.

Conference video: New Methods of Exploring, Analyzing, and Predicting Molecular Interactions

Prof. Art Olson discussed how we understand what we cannot see directly, how we integrate data from different sources, and how to develop software tools to move forward.

Foresight co-founder on the future of the human lifespan

Optimized Geek podcast featured Christine Peterson on the future of nanotechnology, human lifespan, artificial intelligence, finding love, and other topics.

Nanotechnology carries gene editing package into cells

Hijacking a viral method of replicating circular genomes, ball-of-yarn-like DNA clews are used to transport the protein and guide RNA molecules needed for gene editing into the cell nucleus.

DNA nanotechnology guides assembling cells into ‘Organoids’

DNA strands decorating cell membranes like ‘Velcro’ program the adhesion of cells to other cells or to extracellular matrices to build tiny tissue models.

Catalytic micromotors demonstrate carbon dioxide removal from water

A micromotor covered with the enzyme carbonic anhydrase zips through water rapidly converting dissolved carbon dioxide to the bicarbonate ion, which can then be precipitated as calcium carbonate.

Parallel to protein folding improves DNA origami process

Designing a small DNA origami that can fold in several almost equivalent ways demonstrates how understanding and guiding the folding pathway can improve the efficiency of the folding process, potentially leading in more complex situations to higher yields of the desired nanostructure and fewer misfolded structures.

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