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Gaming the Future: The Book!

Category: Atomically Precise Manufacturing (APM)

Computational nanotechnology to benefit from expanded first-principles molecular dynamics

A combination of techniques has made possible the expansion of problems that can be handled by first-principles molecular dynamics from a few hundred atoms to a very large system containing 32,768 atoms.

Preserving protein function in DNA-protein nanostructures

Linking proteins to DNA scaffolds to produce complex functional nanostructures can require chemistry that damages protein function. A new systematic approach avoids exposing proteins to damaging conditions.

Single molecule pump concentrates small molecules

A rotaxane-based single molecule pump combines cycling oxidation-reduction potential of the solution with kinetic barriers to moving backward to concentrate small ring molecules against an energy gradient.

Science and technology roadmaps for nanotechnology

A European Science and Technology Roadmap for Graphene, Related Two-Dimensional Crystals, and Hybrid Systems hints at the opportunities to be harvested from, and the need for, the development of atomically precise manufacturing (APM).

Foresight Institute Awards Feynman Prizes in Nanotechnology to Amanda S. Barnard, Joseph W. Lyding

The Theory Prize was given for research into diamond nanoparticles; the Experimental Prize was given for development of scanning tunneling microscope (STM) technology.

DNA nanoswitches open window on molecular interactions

Positioning two or more molecules along a long DNA strand can cause the DNA molecule to adopt different shapes if the molecules interact. Quickly and cheaply separating these shapes by a simple gel electrophoresis assay provides a wealth of information about how the molecules interact.

New scaffold for nanotechnology engineered from amyloid-like proteins

Design and computational simulation of amyloid proteins of diverse functions from diverse sources enable the self-assembly of proteins that could provide scaffolds for diverse applications.

Cotranscriptional folding of single RNA strand added to nanotechnology toolkit

RNA origami brings new dimensions to nucleic acid nanotechnology by exploiting the much greater variety of RNA structural motifs (compared to DNA) to do what cannot easily be done with DNA origami, like fold into predetermined nanostructures rapidly while being transcribed.

Automated synthesis expands nanotechnology building block repertoire

Iterative coupling, purification, and cyclization of a large collection of organic building blocks promises a vast array of complex small and medium sized molecules as candidates for drug discovery, catalysis, and nanotechnology.

Atomically precise manufacturing as the future of nanotechnology

A commentary over at Gizmodo argues that ideas about molecular manufacturing that sounded like science fiction in 1986 now sound more like science fact.

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